2018
DOI: 10.1186/s12986-018-0284-9
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Abstract: Background Very low carbohydrate (VLC) diets are used to promote weight loss and improve insulin resistance (IR) in obesity. Since the high fat content of VLC diets may predispose to hepatic steatosis and hepatic insulin resistance, we investigated the effect of a VLC weight-reduction diet on measures of hepatic and whole body insulin resistance in obese rats. Methods In Phase 1, adult male Sprague-Dawley rats were made obese by ad libitum consumption of a high-fat (HF1…

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