Vertical One-and-a-Half Syndrome

Coexisting vertical and horizontal one and a half syndromes

“…3 4 Vertical, as distinct from horizontal, one and a half syndrome, has also been documented recently 12 5 6 We report on a patient with concurrent vertical and horizontal one and a half syndromes.…”

“…Attention has recently focused on the rostral interstitial nucleus of the medial longitudinal fasciculus, interstitial nucleus of Cajal, and posterior commissure, all located in the tegmentum of the mesencephalon, as the brain stem centres for vertical eye movement 12 Vertical one and a half syndrome consists of a bilateral conjugate upgaze palsy and a unilateral downward palsy,2 5 or a bilateral conjugate downward palsy and a monocular upgaze palsy 6. It has been reported that the fibres involved in upward gaze from the posterior commissure may explain bilateral upgaze palsy, and the fibres involved in downward gaze may be affected on one side before their decussation in contralateral lesion, or after their decussation in ipsilateral lesion 2.…”

Coexisting vertical and horizontal one and a half syndromes

“…3 4 Vertical, as distinct from horizontal, one and a half syndrome, has also been documented recently 12 5 6 We report on a patient with concurrent vertical and horizontal one and a half syndromes.…”

“…Attention has recently focused on the rostral interstitial nucleus of the medial longitudinal fasciculus, interstitial nucleus of Cajal, and posterior commissure, all located in the tegmentum of the mesencephalon, as the brain stem centres for vertical eye movement 12 Vertical one and a half syndrome consists of a bilateral conjugate upgaze palsy and a unilateral downward palsy,2 5 or a bilateral conjugate downward palsy and a monocular upgaze palsy 6. It has been reported that the fibres involved in upward gaze from the posterior commissure may explain bilateral upgaze palsy, and the fibres involved in downward gaze may be affected on one side before their decussation in contralateral lesion, or after their decussation in ipsilateral lesion 2.…”

Detection of third and sixth cranial nerve palsies with a novel method for eye tracking while watching a short film clip

“…7 Monocular paresis of ocular elevation can occur in patients with lesions near the posterior commissure, but this is very rare and does not supervene in cases of midbrain compression from the mass effect of supratentorial lesions. 2,14,28 …”

Vertical one-and-a-half syndrome with horizontal internuclear ophthalmoplegia and bilateral supranuclear ptosis in rostral midbrain and medial thalamic stroke

“…The classical horizontal one-and-a-half syndrome is caused by a lesion involving the MLF and the ipsilateral abducens nucleus or the paramedian pontine reticular formation 1. The vertical one-and-a-half syndrome is characterised by bilateral conjugate upgaze palsy and a unilateral downward palsy2 3 or a bilateral conjugate downward palsy and a unilateral upgaze palsy 4. This syndrome is caused by a rostral midbrain lesion affecting the rostral interstitial nucleus of the MLF and the posterior commissure (figure 3a–c).…”

Coexisting vertical and horizontal one and a half syndromes

“…3 4 Vertical, as distinct from horizontal, one and a half syndrome, has also been documented recently 12 5 6 We report on a patient with concurrent vertical and horizontal one and a half syndromes.…”

“…Attention has recently focused on the rostral interstitial nucleus of the medial longitudinal fasciculus, interstitial nucleus of Cajal, and posterior commissure, all located in the tegmentum of the mesencephalon, as the brain stem centres for vertical eye movement 12 Vertical one and a half syndrome consists of a bilateral conjugate upgaze palsy and a unilateral downward palsy,2 5 or a bilateral conjugate downward palsy and a monocular upgaze palsy 6. It has been reported that the fibres involved in upward gaze from the posterior commissure may explain bilateral upgaze palsy, and the fibres involved in downward gaze may be affected on one side before their decussation in contralateral lesion, or after their decussation in ipsilateral lesion 2.…”

Detection of third and sixth cranial nerve palsies with a novel method for eye tracking while watching a short film clip

“…7 Monocular paresis of ocular elevation can occur in patients with lesions near the posterior commissure, but this is very rare and does not supervene in cases of midbrain compression from the mass effect of supratentorial lesions. 2,14,28 …”

Vertical one-and-a-half syndrome with horizontal internuclear ophthalmoplegia and bilateral supranuclear ptosis in rostral midbrain and medial thalamic stroke

“…The classical horizontal one-and-a-half syndrome is caused by a lesion involving the MLF and the ipsilateral abducens nucleus or the paramedian pontine reticular formation 1. The vertical one-and-a-half syndrome is characterised by bilateral conjugate upgaze palsy and a unilateral downward palsy2 3 or a bilateral conjugate downward palsy and a unilateral upgaze palsy 4. This syndrome is caused by a rostral midbrain lesion affecting the rostral interstitial nucleus of the MLF and the posterior commissure (figure 3a–c).…”

Coexisting vertical and horizontal one and a half syndromes

“…3 4 Vertical, as distinct from horizontal, one and a half syndrome, has also been documented recently 12 5 6 We report on a patient with concurrent vertical and horizontal one and a half syndromes.…”

“…Attention has recently focused on the rostral interstitial nucleus of the medial longitudinal fasciculus, interstitial nucleus of Cajal, and posterior commissure, all located in the tegmentum of the mesencephalon, as the brain stem centres for vertical eye movement 12 Vertical one and a half syndrome consists of a bilateral conjugate upgaze palsy and a unilateral downward palsy,2 5 or a bilateral conjugate downward palsy and a monocular upgaze palsy 6. It has been reported that the fibres involved in upward gaze from the posterior commissure may explain bilateral upgaze palsy, and the fibres involved in downward gaze may be affected on one side before their decussation in contralateral lesion, or after their decussation in ipsilateral lesion 2.…”

Detection of third and sixth cranial nerve palsies with a novel method for eye tracking while watching a short film clip

“…7 Monocular paresis of ocular elevation can occur in patients with lesions near the posterior commissure, but this is very rare and does not supervene in cases of midbrain compression from the mass effect of supratentorial lesions. 2,14,28 …”

Vertical one-and-a-half syndrome with horizontal internuclear ophthalmoplegia and bilateral supranuclear ptosis in rostral midbrain and medial thalamic stroke

“…The classical horizontal one-and-a-half syndrome is caused by a lesion involving the MLF and the ipsilateral abducens nucleus or the paramedian pontine reticular formation 1. The vertical one-and-a-half syndrome is characterised by bilateral conjugate upgaze palsy and a unilateral downward palsy2 3 or a bilateral conjugate downward palsy and a unilateral upgaze palsy 4. This syndrome is caused by a rostral midbrain lesion affecting the rostral interstitial nucleus of the MLF and the posterior commissure (figure 3a–c).…”