Vertical bone augmentation induced by ultrathin hydroxyapatite sputtered coated mini titanium implants in a rabbit calvaria model

Abstract

The present results indicated that sputtered HA-coated titanium implant together with collagen membrane could be a novel and effective approach for vertical bone augmentation.

A doxycycline‐treated hydroxyapatite implant surface attenuates the progression of peri‐implantitis: A radiographic and histological study in mice

“…This issue was ameliorated at the beginning of the 21st century. As HA‐coated surfaces are highly osteoconductive and promote implant stability at the early phase after implant placement, several HA‐coated surfaces were developed . In the present study, the surface was modified with magnetron sputtering technology, which produces strong, uniform and thin HA adhesion to the implant surface.…”

“…Hydroxyapatite (HA) coating is one of the most effective implant surface modifications that accelerates the implant fixation on the adjacent newly formed bone tissues . Thin HA coating fabricated by sputtering technology has been shown to be a promising surface to treat patients with a compromised alveolar bone condition . Furthermore, HA is also useful as a carrier for therapeutic drugs.…”

Enhancement of aptamer immobilization using egg shell-derived nano-sized spherical hydroxyapatite for thrombin detection in neuroclinic

“…Synthetic HA has been extensively applied in biomedical implants [1,2], bone tissue engineering [3,4], drug delivery [5], and stem cell researches [6] owing to its excellent biocompatibility, bioactivity, porous structure and multi-adsorbing sites.…”

Promotion of bone regeneration on titanium implants through a chemical treatment process using calcium phosphate slurry: Microscopic analysis, cellular response, and animal experiment

“…The difference in the surface between these specimens was a thin HAp layer, as seen in Figure ; therefore, it was obvious that the thin HAp layer formed via the slurry treatment promoted bone regeneration on the Ti implants. Thus far, many studies have demonstrated that bone formation is active on a HAp layer compared to a pure Ti surface in the early stage . The HAp layer formed in this study was not a homogeneous layer but a thin layer with an island‐like structure, yet the biological advantage of extensive bone formation could be obtained similarly.…”

“…Thus far, many studies have demonstrated that bone formation is active on a HAp layer compared to a pure Ti surface in the early stage. [23][24][25] The HAp layer formed in this study was not a homogeneous layer but a thin layer with an island-like structure, yet the biological advantage of extensive bone formation could be obtained similarly. The slurry treatment has great advantages in the manufacturing cost and, furthermore, the layer formed is presumed to have high adhesive strength.…”