Vertebral Metastasis in Gallbladder Carcinoma- An Unusual Site

Gupta, Nikhil; Goswami, Binita; Mahajan, Neha; Dey, Subhajit

doi:10.5171/2012.165756

Cited by 4 publications

(8 citation statements)

References 5 publications

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“…Skeletal metastases in carcinoma gallbladder are very rare, with only few case reports of bone metastasis in carcinoma gall bladder at the time of presentation. 28…”

Section: Discussionmentioning

confidence: 99%

Carcinoma of gall bladder in Central India – Is there a shifting trend?

Haritha¹,

Rawat

2022

IJMPO

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To evaluate the demographic and clinicopathological profile of patienst with gall bladder cancer. A total of 464 patients of gall bladder cancer were taken in the study from January 2017 till December 2021. Both demographic and clinicopathological data was obtained retrospectively from the medical record database. We found that there is a shift in age group over the period of 5 years with most of the patients previously being in the age group 61–70 years with a recent shift in the last two years to the age group 51-60 years. Majority of the patients were females coming from a rural background. Most of them had a non – vegetarian diet. Addiction in the form of tobacco chewing and smoking was present in 44.8% and 18.7% respectively and alcohol intake was seen in 12.2%. The most common site of disease was found to be involving the body 69.3%. Less commonly the disease was reported at the neck. Almost all patients had adenocarcinoma as the histology with moderate grade of differentiation. 96.7% of pateints presented to us in the advanced stage. Stage IVB presentation was seen in 54.3% of patients. Majority of the patients had a direct and lymphatic mode of dissemination. Presence of gall stone was seen in 36.2% of patients. Pain was the most common presenting symptom followed by jaundice and obstruction. In our country, incidental GBC is fairly underreported due to no active screening program to detect patients with symptomatic gallstones undergoing routine cholecystectomy. These patients can be easily detected if there is a higher index of suspicion prior to, during as well as after surgery.

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“…Skeletal metastases in carcinoma gallbladder are very rare, with only few case reports of bone metastasis in carcinoma gall bladder at the time of presentation. 28…”

Section: Discussionmentioning

confidence: 99%

Carcinoma of gall bladder in Central India – Is there a shifting trend?

Haritha¹,

Rawat

2022

IJMPO

View full text Add to dashboard Cite

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“…The leading modes of dissemination in GBC are lymphatic, vascular, neural, intraperitoneal, and intraductal [9]. The common site of distant metastasis are the liver, abdominal lymph nodes, and peritoneum and rarely to the bowel, cervix, kidney, thyroid, and heart [10][11]. The lung is the most common site of extra-abdominal metastasis [12][13].…”

Section: Discussionmentioning

confidence: 99%

“…Breast metastasis is mostly seen from hematological malignancy, melanoma, and small cell carcinoma of the lung [15]. Metastasis to the breast from the gallbladder is significantly less and account for very few cases [6][7][8][9][10][11][12][13][14][15][16].…”

Section: Discussionmentioning

confidence: 99%

Metastasis to Breast From Carcinoma Gallbladder: A Case Report and Review of Literature

Sahoo

Barik

Mishra

et al. 2020

Cureus

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Gallbladder cancer (GBC) is the commonest malignancy among biliary tract cancers. Locoregional spread in GBC is more common than distant metastasis. The liver and abdominal lymph nodes is the most common site of distant metastasis. Breast metastasis is a rare site of dissemination. GBC is an aggressive tumor and carries a poor prognosis, with a five-year survival rate of less than 10%. Metastasis to the breast from a gallbladder is significantly less and accounts for very few cases. Here, we are reporting a rare case of carcinoma gallbladder metastasis to the breast who survived for 38 months from the diagnosis of GBC and around 25 months after breast metastasis.

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“…Extra abdominal metastasis involves mostly lungs (9,12,18). Rare sites of metastasis have been reported including bone, brain, skin, orbit, and heart (9,(19)(20)(21)(22)(23)(24)(25)(26)(27).…”

Section: Discussionmentioning

confidence: 99%

“…The most common site of dissemination is liver (8,9). Breast metastasis in GBC is an unusual site of dissemination.…”

Section: Introductionmentioning

confidence: 99%

Breast metastasis from recurrent gallbladder adenocarcinoma: a case report with review of the literature

Amarti

Faouzi

Salmi

et al. 2016

J. Gastrointest. Oncol.

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Gallbladder adenocarcinoma has a poor prognostic. The leading modes of dissemination in gallbladder cancer (GBC) are lymphatic, vascular, neural, intraperitoneal, and intraductal. The most common site of dissemination is liver. Breast metastasis in GBC is an unusual site of dissemination. Only few cases have been reported in the literature. We report a rare case of solitary breast metastasis from recurrent gallbladder carcinoma in light of existing literature.

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Vertebral Metastasis in Gallbladder Carcinoma- An Unusual Site

Abstract: Background: Gallbladder carcinoma spreads commonly by direct invasion. Hematogenous spread to liver, lungs, skin are known but vertebral metastasis has rarely been reported earlier.

Cited by 4 publications

References 5 publications

Carcinoma of gall bladder in Central India – Is there a shifting trend?

Carcinoma of gall bladder in Central India – Is there a shifting trend?

Metastasis to Breast From Carcinoma Gallbladder: A Case Report and Review of Literature

Breast metastasis from recurrent gallbladder adenocarcinoma: a case report with review of the literature

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