Verrucous cyst

Rhabdomyomatous Mesenchymal Hamartoma Mimicking Basal Cell Carcinoma

“…9 In the latter, the presence of HPV has been demonstrated. 11,14,15 We found no evidence of the HPV types studied in the seborrheic cyst, and therefore, this supports the concept that it results from a nonviral, epidermal, seborrheic-like change. Nevertheless, we cannot conclude if the seborrheic change happens before or after the formation of the cyst.…”

Odontogenic cyst with verrucous proliferation

“…The rarity of verrucous change in odontogenic cysts suggests that this might not be an entity in itself, but rather that it represents an unusual secondary change in a pre‐existing cyst. It is tempting to implicate a viral aetiology for the epithelial proliferation that has led to the verrucous configuration, similar to the verrucous epidermal cysts which have been shown to have evidence of HPV in the cyst lining (2, 3). Furthermore, verrucous proliferation in an ameloblastoma associated with HPV has been reported (4).…”

Verrucous cyst: Possible precursor of proliferating epidermoid cyst

“…Verrucous cysts were named as such in 1991 due to their characteristic histology in the squamous lining . At that time, however, no human papillomavirus (HPV) antigens were found in the lesions .…”

“…Verrucous cysts were named as such in 1991 due to their characteristic histology in the squamous lining . At that time, however, no human papillomavirus (HPV) antigens were found in the lesions . Kim et al successfully showed HPV type 59 with immunohistochemistry in the wall of a verrucous cyst in 2006, and further studies have shown various HPV genomes (type 20, 34, 8, 6) with polymerase chain reaction …”

“…Regardless of location or associated HPV type, typical histology includes an acanthotic squamous epithelium with characteristic verrucous features, including hypergranulosis with large, dense keratohyaline granules, and occasional koilocytosis. The luminal surface of the cystic epithelium is often papillomatous . Most verrucous cysts are epidermoid/infundibular cysts; however, verrucous trichilemmal cysts have also been reported .…”