VEGFR2 blockade inhibits glioblastoma cell proliferation by enhancing mitochondrial biogenesis
Min Guo,
Junhao Zhang,
Jiang Han
et al.
Abstract:Background
Glioblastoma is an aggressive brain tumor linked to significant angiogenesis and poor prognosis. Anti-angiogenic therapies with vascular endothelial growth factor receptor 2 (VEGFR2) inhibition have been investigated as an alternative glioblastoma treatment. However, little is known about the effect of VEGFR2 blockade on glioblastoma cells per se.
Methods
VEGFR2 expression data in glioma patients were retrieved from the public database T… Show more
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