Vegetable Consumption Is Linked to Decreased Visceral and Liver Fat and Improved Insulin Resistance in Overweight Latino Youth

Cook, Lauren; O’Reilly, Gillian; Goran, Michael I.; Weigensberg, Marc J.; Spruijt‐Metz, Donna; Davis, Jaimie N.

doi:10.1016/j.jand.2014.01.017

Cited by 48 publications

(41 citation statements)

References 38 publications

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“…This strategy could play an important role in weight management. [79][80][81] In a cross-sectional study of 175 overweight Latino youth, nonstarchy vegetables consumption was associated with lower liver fat deposition, 82 increased insulin sensitivity and decreased visceral adipose tissue. Other observational studies supported the notion that NAFLD patients consume less vegetables and dietary fibers than controls.…”

Section: Fruits and Vegetablesmentioning

confidence: 99%

The Mediterranean dietary pattern as the diet of choice for non‐alcoholic fatty liver disease: Evidence and plausible mechanisms

Zelber‐Sagi

Salomone²,

Mlynarsky

2017

Liver International

203

162

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Non-alcoholic fatty liver disease (NAFLD) has become a major global health burden, leading to increased risk for cirrhosis, hepatocellular carcinoma, type-2 diabetes and cardiovascular disease. Lifestyle intervention aiming at weight reduction is the most established treatment. However, changing the dietary composition even without weight loss can also reduce steatosis and improve metabolic alterations as insulin resistance and lipid profile. The Mediterranean diet (MD) pattern has been proposed as appropriate for this goal, and was recommended as the diet of choice for the treatment of NAFLD by the EASL-EASD-EASO Clinical Practice Guidelines. The MD has an established superiority in long term weight reduction over low fat diet, but it improves metabolic status and steatosis even without it.However, the effect on liver inflammation and fibrosis was tested only in few observational studies with positive results. Furthermore, considering the strong association between NAFLD and diabetes and CVD, the MD has a highly established advantage in prevention of these diseases, demonstrated in randomized clinical trials. The individual components of the MD such as olive oil, fish, nuts, whole grains, fruits, and vegetables, have been shown to beneficially effect or negatively correlate with NAFLD, while consumption of components that characterize a Western dietary pattern as soft drinks, fructose, meat and saturated fatty acids have been shown to have detrimental association with NAFLD. In this review we will cover the epidemiological evidence and the plausible molecular mechanisms by which the MD as a whole and each of its components can be of benefit in NAFLD.

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Section: Fruits and Vegetablesmentioning

confidence: 99%

The Mediterranean dietary pattern as the diet of choice for non‐alcoholic fatty liver disease: Evidence and plausible mechanisms

Zelber‐Sagi

Salomone²,

Mlynarsky

2017

Liver International

203

162

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“…In a cross-sectional study in 175 Latino adolescents that included deep metabolic phenotyping, Cook et al (5) found that those who consumed the highest amount of non-starchy vegetables had a 44% lower hepatic fat content compared to those with the lowest intake (5.6±8.7% vs. 10.0±8.5%; p=0.01) (5). Nutrient-rich vegetable (leafy greens and green/orange vegetables) consumers had 31% greater insulin sensitivity and 17% less visceral adipose tissue compared to non-consumers (5).…”

Section: Fruit and Vegetable Intake Incident Type 2 Diabetes And Bimentioning

confidence: 99%

“…Nutrient-rich vegetable (leafy greens and green/orange vegetables) consumers had 31% greater insulin sensitivity and 17% less visceral adipose tissue compared to non-consumers (5). However, total vegetable intake was not associated with fasting glucose, fasting insulin, HOMA-IR, or insulin sensitivity and pancreatic beta-cell function as measured by clamp.…”

Section: Fruit and Vegetable Intake Incident Type 2 Diabetes And Bimentioning

confidence: 99%

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Prevention of metabolic diseases

Kuzma

Schmidt

Kratz

2017

Current Opinion in Clinical Nutrition &Amp; Metabolic Care

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Purpose of review To discuss recent evidence from observational and intervention studies on the relationship between fruit and vegetable consumption and metabolic disease. Recent findings Observational studies have consistently demonstrated a modest inverse association between the intake of fruit and leafy green vegetables, but not total vegetables, and biomarkers of metabolic disease as well as incident type 2 diabetes mellitus. This is in contrast to limited evidence from recently published randomized controlled dietary intervention trials, which – in sum - suggest little to no impact of increased fruit and vegetable consumption on biomarkers of metabolic disease. Summary Evidence from observational studies that fruit and leafy green vegetable intake is associated with lower type 2 diabetes risk and better metabolic health could not be confirmed by dietary intervention trials. It is unclear whether this discrepancy is due to limitations inherent in observational studies (e.g., subjective dietary assessment methods, residual confounding), or due to limitations in the few available intervention studies (e.g., short duration of follow-up, interventions combining whole fruit and fruit juice, or lack of compliance). Future studies that attempt to address these limitations are needed to provide more conclusive insight into the impact of fruit and vegetable consumption on metabolic health.

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“…Satu lagi penyelidikan telah menunjukkan hubungan yang positif antara pengambilan sayur-sayuran yang kaya dengan nutrien dengan sensitiviti insulin (Cook et al 2014). Kajian yang sama juga telah menunjukkan lemak viseral dapat dikurangkan dengan pengambilan sayur-sayuran yang kaya dengan nutrien.…”

Section: Pengambilan Sayur-sayuranunclassified