Vasodilators and vasoactive substances for idiopathic sudden sensorineural hearing loss

Effectiveness of electroacupuncture for the treatment of sudden sensorineural hearing loss

“…Although a variety of treatment modalities are utilized for the treatment of patients with SSNHL, its optimal therapy strategy has not been established, because of its uncertain etiology. Acupuncture, TENS, and EA are reported to manage symptoms of SSNHL [19–27] . In addition, EA as a combination of acupuncture and TENS may benefit patients with TENS [26–27] .…”

“…Acupuncture, TENS, and EA are reported to manage symptoms of SSNHL. [19][20][21][22][23][24][25][26][27] In addition, EA as a combination of acupuncture and TENS may benefit patients with TENS. [26][27] However, there is seldom clinical evidence to explore and support this issue.…”

Effectiveness of electroacupuncture for the treatment of sudden sensorineural hearing loss

“…Although a variety of treatment modalities are utilized for the treatment of patients with SSNHL, its optimal therapy strategy has not been established, because of its uncertain etiology. Acupuncture, TENS, and EA are reported to manage symptoms of SSNHL [19–27] . In addition, EA as a combination of acupuncture and TENS may benefit patients with TENS [26–27] .…”

“…Acupuncture, TENS, and EA are reported to manage symptoms of SSNHL. [19][20][21][22][23][24][25][26][27] In addition, EA as a combination of acupuncture and TENS may benefit patients with TENS. [26][27] However, there is seldom clinical evidence to explore and support this issue.…”

Coagulation States in Patients With Sudden Sensorineural Hearing Loss Evaluated by Thromboelastography

“…In fact, there are no reliable studies to confirm that defibrinogenation therapy is superior to steroid therapy. The 2019 clinical practice guideline from the American Academy of Otolaryngology–Head and Neck Surgery strongly recommends against the routine use of thrombolytics and vasoactive substances 1,5,33–35 . The guideline considered that existing studies have a high risk of bias because their overall methodology was poor and sample sizes were small.…”

“…The 2019 clinical practice guideline from the American Academy of Otolaryngology-Head and Neck Surgery strongly recommends against the routine use of thrombolytics and vasoactive substances. 1,5,[33][34][35] The guideline considered that existing studies have a high risk of bias because their overall methodology was poor and sample sizes were small. As mentioned, in this study, CCT and TEG results are normal, which indicate that patients with SSNHL are not in a hypercoagulable state.…”

Controversies in the management of sudden sensorineural hearing loss: an evidence‐based review

“…A Cochrane review from 2010 identified only three RCTs that examined Carbogen, Prostoglandin E1 and naftidrofuryl with Dextran . Prostoglandin E1 showed no benefit in mean hearing thresholds although there was benefit in high‐frequency hearing gain and an improvement in tinnitus.…”

Effectiveness of electroacupuncture for the treatment of sudden sensorineural hearing loss

“…Although a variety of treatment modalities are utilized for the treatment of patients with SSNHL, its optimal therapy strategy has not been established, because of its uncertain etiology. Acupuncture, TENS, and EA are reported to manage symptoms of SSNHL [19–27] . In addition, EA as a combination of acupuncture and TENS may benefit patients with TENS [26–27] .…”

“…Acupuncture, TENS, and EA are reported to manage symptoms of SSNHL. [19][20][21][22][23][24][25][26][27] In addition, EA as a combination of acupuncture and TENS may benefit patients with TENS. [26][27] However, there is seldom clinical evidence to explore and support this issue.…”

Coagulation States in Patients With Sudden Sensorineural Hearing Loss Evaluated by Thromboelastography

“…In fact, there are no reliable studies to confirm that defibrinogenation therapy is superior to steroid therapy. The 2019 clinical practice guideline from the American Academy of Otolaryngology–Head and Neck Surgery strongly recommends against the routine use of thrombolytics and vasoactive substances 1,5,33–35 . The guideline considered that existing studies have a high risk of bias because their overall methodology was poor and sample sizes were small.…”

“…The 2019 clinical practice guideline from the American Academy of Otolaryngology-Head and Neck Surgery strongly recommends against the routine use of thrombolytics and vasoactive substances. 1,5,[33][34][35] The guideline considered that existing studies have a high risk of bias because their overall methodology was poor and sample sizes were small. As mentioned, in this study, CCT and TEG results are normal, which indicate that patients with SSNHL are not in a hypercoagulable state.…”

Controversies in the management of sudden sensorineural hearing loss: an evidence‐based review

“…A Cochrane review from 2010 identified only three RCTs that examined Carbogen, Prostoglandin E1 and naftidrofuryl with Dextran . Prostoglandin E1 showed no benefit in mean hearing thresholds although there was benefit in high‐frequency hearing gain and an improvement in tinnitus.…”

Effectiveness of electroacupuncture for the treatment of sudden sensorineural hearing loss

“…Although a variety of treatment modalities are utilized for the treatment of patients with SSNHL, its optimal therapy strategy has not been established, because of its uncertain etiology. Acupuncture, TENS, and EA are reported to manage symptoms of SSNHL [19–27] . In addition, EA as a combination of acupuncture and TENS may benefit patients with TENS [26–27] .…”

“…Acupuncture, TENS, and EA are reported to manage symptoms of SSNHL. [19][20][21][22][23][24][25][26][27] In addition, EA as a combination of acupuncture and TENS may benefit patients with TENS. [26][27] However, there is seldom clinical evidence to explore and support this issue.…”

Coagulation States in Patients With Sudden Sensorineural Hearing Loss Evaluated by Thromboelastography

“…In fact, there are no reliable studies to confirm that defibrinogenation therapy is superior to steroid therapy. The 2019 clinical practice guideline from the American Academy of Otolaryngology–Head and Neck Surgery strongly recommends against the routine use of thrombolytics and vasoactive substances 1,5,33–35 . The guideline considered that existing studies have a high risk of bias because their overall methodology was poor and sample sizes were small.…”

“…The 2019 clinical practice guideline from the American Academy of Otolaryngology-Head and Neck Surgery strongly recommends against the routine use of thrombolytics and vasoactive substances. 1,5,[33][34][35] The guideline considered that existing studies have a high risk of bias because their overall methodology was poor and sample sizes were small. As mentioned, in this study, CCT and TEG results are normal, which indicate that patients with SSNHL are not in a hypercoagulable state.…”

Controversies in the management of sudden sensorineural hearing loss: an evidence‐based review

“…A Cochrane review from 2010 identified only three RCTs that examined Carbogen, Prostoglandin E1 and naftidrofuryl with Dextran . Prostoglandin E1 showed no benefit in mean hearing thresholds although there was benefit in high‐frequency hearing gain and an improvement in tinnitus.…”