Vascularized platforms for investigating cell communication via extracellular vesicles
Junyoung Kim,
Jooyoung Ro,
Yoon-Kyoung Cho
Abstract:The vascular network plays an essential role in the maintenance of all organs in the body via the regulated delivery of oxygen and nutrients, as well as tissue communication via the transfer of various biological signaling molecules. It also serves as a route for drug administration and affects pharmacokinetics. Due to this importance, engineers have sought to create physiologically relevant and reproducible vascular systems in tissue, considering cell–cell and extracellular matrix interaction with structural … Show more
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