Vascular disease prevalence in diabetic patients in China: standardised comparison with the 14 centres in the WHO multinational study of vascular disease in diabetes

Abstract

We compare the prevalence of vascular disease and associated risk factors in a Chinese diabetic cohort with the results from the WHO Multinational Study of Vascular Disease in Diabetes (WHO MSVDD) which involved 14 centres from 13 countries [3]. Results. Compared with the WHO MSVDD centres, the Chinese cohort was slightly older, had a shorter duration of known diabetes and had fewer insulintreated patients. Arterial pressure, total blood cholesterol and body mass index were substantially lower. Large vessel disease rate for age, sex and duration adjusted data (17.9 %) was about half that of the combined WHO MSVDD centres (33.5 % p < 0.001). However, retinopathy (47.4 % vs 35.8 % p < 0.001) and proteinuria (57.1 vs 24.9 % p < 0.001) rates were significantly higher. Conclusion/interpretation. Relatively low arterial pressures and blood cholesterol are likely contributors to the notably low arterial disease rates in this Chinese diabetic cohort; they reflect low rates in the Chinese mainland general population and resemble the Tokyo and Hong Kong centres of the WHO MSVDD. The high rates of retinopathy and proteinuria could relate to later diagnosis, degree of hyperglycaemia and/or increased susceptibiltiy to microangiopathy. [Diabetologia (2001) Methods

Incidence, prevalence and coronary heart disease risk level in known Type 2 diabetes: a sentinel practice network study in the Basque Country, Spain

“…The prevalence of Type 2 diabetic complications in our study is similar to that described previously in Spain in the last decade [51,52,53,54,55,56,57,58,59,60,61,62], and in the WHO Multinational Study of Vascular Disease in Diabetes (WHO MSVDD) [63]. However, in a recent study in China, the prevalence of microvascular complications was higher and the prevalence of macrovascular disease was lower than in the previous studies [64]. The high rates of retinopathy (47%) and proteinuria (57%) found in China could be related to later diagnosis, degree of hyperglycaemia, and/or increased susceptibility to microangiopathy.…”

“…The high rates of retinopathy (47%) and proteinuria (57%) found in China could be related to later diagnosis, degree of hyperglycaemia, and/or increased susceptibility to microangiopathy. The low prevalence of cardiovascular risk factors is a likely contributor to the low rates of arterial disease (<20%) in the Chinese diabetic cohort, and resembles the Tokyo and Hong Kong centres of the WHO MSVDD [63,64]. In our study, total large vessel disease and nephropathy in men exceeded that in women.…”

“…In our study, total large vessel disease and nephropathy in men exceeded that in women. However in the WHO MSVDD [63] and in the Chinese sample [64] the prevalence of macroangiopathy was higher in women than in men. The higher CHD risk that we have found in Type 2 diabetic men is in agreement with the higher prevalence of macroangiopathy found in our Type 2 diabetic men.…”

Prevalence of diabetes and impaired fasting glucose in the Chinese adult population: International Collaborative Study of Cardiovascular Disease in Asia (InterASIA)

“…Diabetes increases the risk of micro-and macrovascular complications in the general population and results in an enormous economic burden to society [1,2,7,14,15]. In addition, impaired fasting glucose and impaired glucose tolerance have been identified as risk factors for overt diabetes and cardiovascular disease [16,17,18].…”

The Role of Triglyceride in Cardiovascular Disease in Asian Patients with Type 2 Diabetes - A Systematic Review

“…The prevalence of CVD in the Asian diabetes population was known to be lower than in Caucasians [5,6]. In the early 1970s, renal failure and stroke were the leading causes of death in diabetic patients in China, Japan, and Pima India, compared with ischemic heart disease in Caucasian patients [6].…”