Vascular Bed of the Retina in Mental Disease

Microvascular anomaly conditions in psychiatric disease. Schizophrenia – angiogenesis connection

“…This may be explained, at least in part, by differences in the brain regions studied, by methodological differences, and by the complexity of surveying the microvasculature in cerebral cortical tissue quantitatively. Early reports suggested abnormalities in the microvasculature in SZ, such as reduction of retinal vascular bed during progressive course of SZ (Cotton et al, 1940) and generally simplified angio-architecture with reduced arborization of the brain vessels in the orbito-frontal cortex of paranoid hallucinatory SZ individuals (Senitz and Winkelmann, 1991). Wide-spread small vessel disease in the cerebral white matter with small foci of demyelination has been shown in patients with SZ psychosis (Bruton et al, 1994).…”

Microvascular anomaly conditions in psychiatric disease. Schizophrenia – angiogenesis connection

“…This may be explained, at least in part, by differences in the brain regions studied, by methodological differences, and by the complexity of surveying the microvasculature in cerebral cortical tissue quantitatively. Early reports suggested abnormalities in the microvasculature in SZ, such as reduction of retinal vascular bed during progressive course of SZ (Cotton et al, 1940) and generally simplified angio-architecture with reduced arborization of the brain vessels in the orbito-frontal cortex of paranoid hallucinatory SZ individuals (Senitz and Winkelmann, 1991). Wide-spread small vessel disease in the cerebral white matter with small foci of demyelination has been shown in patients with SZ psychosis (Bruton et al, 1994).…”

Microvascular anomaly conditions in psychiatric disease. Schizophrenia – angiogenesis connection

“…This may be explained, at least in part, by differences in the brain regions studied, by methodological differences, and by the complexity of surveying the microvasculature in cerebral cortical tissue quantitatively. Early reports suggested abnormalities in the microvasculature in SZ, such as reduction of retinal vascular bed during progressive course of SZ (Cotton et al, 1940) and generally simplified angio-architecture with reduced arborization of the brain vessels in the orbito-frontal cortex of paranoid hallucinatory SZ individuals (Senitz and Winkelmann, 1991). Wide-spread small vessel disease in the cerebral white matter with small foci of demyelination has been shown in patients with SZ psychosis (Bruton et al, 1994).…”

Microvascular anomaly conditions in psychiatric disease. Schizophrenia – angiogenesis connection

“…This may be explained, at least in part, by differences in the brain regions studied, by methodological differences, and by the complexity of surveying the microvasculature in cerebral cortical tissue quantitatively. Early reports suggested abnormalities in the microvasculature in SZ, such as reduction of retinal vascular bed during progressive course of SZ (Cotton et al, 1940) and generally simplified angio-architecture with reduced arborization of the brain vessels in the orbito-frontal cortex of paranoid hallucinatory SZ individuals (Senitz and Winkelmann, 1991). Wide-spread small vessel disease in the cerebral white matter with small foci of demyelination has been shown in patients with SZ psychosis (Bruton et al, 1994).…”