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“…OCT-A has confirmed the presence of extensive occlusions of the choriocapillaris in APMPPE [34]. The marked under-perfusion of the choriocapillaris in inflammatory diseases of the choroid such as APMPPE simultaneously promotes the development of secondary choroidal neovascularisation (CNV) [32].…”
Section: Choroidal Blood Flow In Inflammatory Diseases Of the Choroidmentioning
“…Any local inflammatory disease of the choroid that results in impairment of the capillary bed by infiltration or compression can lead secondarily to ischaemia and reduced supply to the outer retina [32]. In such cases it is often not possible to clearly differentiate clinically whether the vascular problem is primary or secondary.…”
Section: Choroidal Blood Flow In Inflammatory Diseases Of the Choroidmentioning
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“…Nonperfusion at the level of the choroid or choriocapillaris secondary to inflammation can cause accumulation of subretinal fluid related to ischemia in the outer retina and RPE. 58 The presence of hypofluorescent dark spots and fuzzy choroidal vessels demonstrated by ICGA suggested choroidal vascular changes in eyes with active Behçet's uveitis. 59 Both acute posterior multifocal placoid pigment epitheliopathy (APMPPE) and multiple evanescent white dot syndrome (MEWDS) are thought to involve inner choroiditis since hypofluorescence in latephase ICGA has been observed.…”
Section: Intraocular Inflammationmentioning