Variations in Cannabis Use Level and Correlates in Opiate-Users on Methadone Maintenance Treatment: A French Prospective Study

Mayet, Aurélie; Lions, C.; Roux, Perrine; Mora, Marion; Maradan, Gwenaëlle; Morel, Alain; Laurent, Michel; Marimoutou, Catherine; Carrieri, Patrizia

doi:10.1016/j.jsat.2015.06.015

Cited by 11 publications

(5 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, level of education was the only sociodemographic factor that was significantly associated with cannabis use whereby, university education was associated with reduced odds of using cannabis during follow-up. This could be due to the observation of low education attainment among participants with the majority (51%) having primary education, a finding similar to what has been observed in regional studies in Tanzania [ 33 , 34 ] and other parts of the world [ 19 , 45 ]. This may reflect the poor education attainment associated with cannabis use [ 46 , 47 ].…”

Section: Discussionsupporting

confidence: 75%

The prevalence and pattern of cannabis use among patients attending a methadone treatment clinic in Nairobi, Kenya

Ngarachu

Kiburi

Owiti

et al. 2022

Subst Abuse Treat Prev Policy

View full text Add to dashboard Cite

Background Cannabis use during methadone treatment may negatively impact treatment outcomes. The aim of this study was to determine the prevalence and pattern of cannabis use among patients attending a methadone treatment clinic in Nairobi, Kenya. Methods This was a retrospective study of 874 patients on methadone therapy at a methadone maintenance treatment clinic in Nairobi, Kenya from December 2014 to November 2018. Data on sociodemographic characteristics and drug use patterns based on urine drug screens was collected from patient files. Data was analyzed using Statistical Package for the Social Sciences (SPSS) for windows version 23.0. Results Point prevalence of cannabis use was 85.8% (95% CI, 83.3 – 88.0) at baseline and 62.7% (95% CI, 59.5 – 65.8) during follow-up. A pattern of polysubstance use was observed where opioids, cannabis and benzodiazepines were the most commonly used drugs. The mean age of the patients was 35.3 (SD 9.0) years with the majority being male, unemployed (76%), (51.4%) had reached primary level of education, and (48.5%) were divorced or separated. University education was associated with reduced risk for cannabis use OR = 0.1 (95% CI, 0.02-0.8, p = 0.031). Conclusion Cannabis use is prevalent among patients attending a methadone treatment clinic in Kenya, suggesting need for targeted interventions to address the problem of cannabis use during methadone treatment.

show abstract

Section: Discussionsupporting

confidence: 75%

The prevalence and pattern of cannabis use among patients attending a methadone treatment clinic in Nairobi, Kenya

Ngarachu

Kiburi

Owiti

et al. 2022

Subst Abuse Treat Prev Policy

View full text Add to dashboard Cite

show abstract

“…Throughout the history of methadone administration, patients have reported that cannabis provides relief from opioid withdrawal symptoms, as well as breakthrough pain and anxiety. 119 However, other evidence demonstrates that cannabis does not relieve withdrawal symptoms for individuals undergoing methadone tapering, and some participants even reported increased severity of their withdrawal symptoms. 104 All the participants in the latter study procured their own cannabis and reported smoking as the route of administration.…”

Section: Shortcomings Of Cannabis In Medication-assisted Therapymentioning

confidence: 99%

Emerging Evidence for Cannabis' Role in Opioid Use Disorder

Wiese

Wilson-Poe

2018

Cannabis and Cannabinoid Research

127

View full text Add to dashboard Cite

Introduction: The opioid epidemic has become an immense problem in North America, and despite decades of research on the most effective means to treat opioid use disorder (OUD), overdose deaths are at an all-time high, and relapse remains pervasive.Discussion: Although there are a number of FDA-approved opioid replacement therapies and maintenance medications to help ease the severity of opioid withdrawal symptoms and aid in relapse prevention, these medications are not risk free nor are they successful for all patients. Furthermore, there are legal and logistical bottlenecks to obtaining traditional opioid replacement therapies such as methadone or buprenorphine, and the demand for these services far outweighs the supply and access. To fill the gap between efficacious OUD treatments and the widespread prevalence of misuse, relapse, and overdose, the development of novel, alternative, or adjunct OUD treatment therapies is highly warranted. In this article, we review emerging evidence that suggests that cannabis may play a role in ameliorating the impact of OUD. Herein, we highlight knowledge gaps and discuss cannabis' potential to prevent opioid misuse (as an analgesic alternative), alleviate opioid withdrawal symptoms, and decrease the likelihood of relapse.Conclusion: The compelling nature of these data and the relative safety profile of cannabis warrant further exploration of cannabis as an adjunct or alternative treatment for OUD.

show abstract

“…Higher education may positively influence substance use behaviour through factors such as enhanced self-efficacy (46). A study in France among patients on MMT found that, low educational level was associated with increased cannabis use daily (51). Alternatively, the association between cannabis use and poor educational achievement could be due to a reverse causal association whereby poor educational achievement leads to increased cannabis use (49).…”

Section: Association Of Sociodemographic Characteristics and Cannabis Usementioning

confidence: 99%

The Prevalence and Pattern of Cannabis Use Among Patients Attending a Methadone Treatment Clinic in Nairobi, Kenya

Ngarachu¹,

Kiburi

Owiti

et al. 2021

Preprint

View full text Add to dashboard Cite

Background: Cannabis use during methadone treatment may negatively impact treatment outcomes. The aim of this study was to determine the prevalence and pattern of cannabis use among patients attending a methadone treatment clinic in Nairobi, Kenya. Methods: This was a retrospective study of 874 patients on methadone therapy at a methadone maintenance treatment clinic in Nairobi, Kenya from December 2014 to November 2018. Data on sociodemographic characteristics and drug use patterns based on urine drug screens was collected from patient files. Data was analyzed using Statistical Package for the Social Sciences (SPSS) for windows version 23.0. Results: Prevalence of cannabis use was 85.8% (95% CI, 83.3 – 88.0) at baseline and 62.7% (95% CI, 59.5 – 65.8) during follow up. A pattern of polysubstance use was observed where opioids, cannabis and benzodiazepines were the most commonly used drugs. The mean age of the patients was 35.3 (SD 9.0) years with majority being male, unemployed (76%), had primary level of education (51.4%) and divorced or separated (48.5%). Cannabis use was associated with dropping out of treatment (p=0.001) and university education was associated with reduced risk for cannabis use OR=0.1 (95% CI, 0.02-0.8, p=0.031). Conclusion: Cannabis use is prevalent among patients attending a methadone treatment clinic in Kenya and is associated with dropping out of treatment. There is a need for targeted interventions to address the problem of cannabis use during methadone maintenance treatment in Nairobi, Kenya.

show abstract

Variations in Cannabis Use Level and Correlates in Opiate-Users on Methadone Maintenance Treatment: A French Prospective Study

Cited by 11 publications

References 35 publications

The prevalence and pattern of cannabis use among patients attending a methadone treatment clinic in Nairobi, Kenya

The prevalence and pattern of cannabis use among patients attending a methadone treatment clinic in Nairobi, Kenya

Emerging Evidence for Cannabis' Role in Opioid Use Disorder

The Prevalence and Pattern of Cannabis Use Among Patients Attending a Methadone Treatment Clinic in Nairobi, Kenya

Contact Info

Product

Resources

About