Variable Vocal Cord Dysfunction Presenting as Wheezing and Exercise-Induced Asthma

Kivity, Shmuel; Bibi, Haim; Schwarz, Yehuda; Greif, Yoel; Topilsky, M; Tabachnick, Elvin

doi:10.3109/02770908609073167

Cited by 50 publications

(29 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The increased odds ratio for females having EILOs corroborated that reported cases predominantly concerns females [13][14][15][16][17][18][19][20][21][22]. The reason for this is not known, but the significantly higher odds ratio for females with symptoms participating on day 2 could partly explain this.…”

Section: Common Sensitivity Common Sensitivitysupporting

confidence: 75%

Exercise-induced laryngeal obstructions: prevalence and symptoms in the general public

Christensen

Thomsen

Rasmussen

et al. 2011

Eur Arch Otorhinolaryngol

141

135

View full text Add to dashboard Cite

Respiratory difficulties caused by exercise-induced laryngeal obstructions (EILOs) are reported with increasing frequency. The aim of this study was to assess the prevalence and symptoms of EILOs and their relation to airway hyperresponsiveness (AHR). In total, 556 randomly selected youths in Copenhagen aged 14-24 years were invited over a 2-year period. The study included a mailed questionnaire and two visits: day 1 (an interview-based questionnaire, methacholine bronchial provocation test and physical exertion test); and day 2 [an exercise test with continuous laryngoscopic recordings (CLE test)]. The diagnosis of EILOs was based on the CLE test. In total, 237 answered the mailed questionnaire and 150 participated on day 1 whereof 98 participated on day 2 also. AHR was verified in 23 (4.1% of invitees) and EILOs in 42 (7.5% of invitees). Co-morbidity was verified in 6 cases (26.1% of verified AHR cases). No symptoms were found specific for either AHR or EILOs. The minimum prevalence of EILOs in this cohort was 7.5%. EILOs were verified in 26.1% of participants with AHR. Questionnaires could not differentiate between AHR and EILOs.

show abstract

Section: Common Sensitivity Common Sensitivitysupporting

confidence: 75%

Exercise-induced laryngeal obstructions: prevalence and symptoms in the general public

Christensen

Thomsen

Rasmussen

et al. 2011

Eur Arch Otorhinolaryngol

141

135

View full text Add to dashboard Cite

show abstract

“…Patient history for PVCD typically consists of sporadic attacks of stridor or wheezing, frequently during activity. 4,5 This often creates confusion among physicians who care for these patients, and many are diagnosed as having reactive airway disease and undergo extended bronchodilator and corticosteroid therapy. 6,7 These patients typically have normal pulse oximetry, blood gas values, and chest radiographs, and do not respond to histamine or methacholine challenges.…”

Section: Discussionmentioning

confidence: 99%

Paradoxical Vocal Cord Dysfunction in Juveniles

Powell¹,

Karanfilov²,

Beechler³

et al. 2000

Arch Otolaryngol Head Neck Surg

138

106

View full text Add to dashboard Cite

Objective: To evaluate demographic and videolaryngoscopic features in a large series of juveniles with paradoxical vocal cord dysfunction (PVCD).Design: Case series data from videolaryngoscopic tapes retrospectively evaluated in a masked, controlled fashion, and demographic data collected via retrospective medical chart review.Setting: A tertiary care otolaryngology and speech pathology referral center.Patients: Twenty-two patients with PVCD aged 18 years and younger diagnosed as having PVCD at The Ohio State University Voice Institute, Columbus.Main Outcome Measures: Age, sex, social history, and medical history (demographic); epiglottic position, arytenoid and interarytenoid appearance, phase 0 stability, true vocal cord respiratory motion, degree of anteroposterior (AP) constriction, and false vocal cord adduction (videolaryngoscopic).Results: Of 22 patients, 18 were girls, and 12 had significant social stressors, particularly organized sports. Nineteen patients had posterior laryngeal changes commonly found in gastroesophageal reflux disease. Twelve patients demonstrated abnormal true vocal cord adduction during quiet respiration. Seven patients demonstrated supraglottic anteroposterior constriction and false vocal cord approximation during phonation. Conclusions:Juvenile PVCD is more common in girls and is associated with social stresses. Anatomic laryngeal changes typically associated with gastroesophageal reflux disease are extremely common in these patients. Juveniles with PVCD frequently demonstrate abnormal true vocal cord adduction during quiet respiration. We recommend that initial evaluation of juvenile patients for possible PVCD be conducted via transnasal fiberoptic laryngoscopy while the patient is asymptomatic, and that strong consideration be given to empiric pharmacological treatment of gastroesophageal reflux disease in juveniles diagnosed as having PVCD.

show abstract

“…PVFD associated with exercise is frequently misdiagnosed as poorly controlled asthma [6]. Many of these patients are asymptomatic at rest and require exercise challenge to elicit symptoms and vocal fold dysfunction [7][8][9][10][11][12]. Some previous treatments of PVFD indicated in the literature have included use of bronchodilators, steroids, reflux medications, anti-allergens, and certain behavioral strategies such as panting [13], developing self-awareness of breathing and other breathing techniques such as ''wide-open'' breathing and what some clinicians call ''diaphragmatic breathing [14].''…”

Section: Introductionmentioning

confidence: 99%

Inspiratory muscle strength training with behavioral therapy in a case of a rower with presumed exercise-induced paradoxical vocal-fold dysfunction

Ruddy

Davenport

Baylor

et al. 2004

International Journal of Pediatric Otorhinolaryngology

View full text Add to dashboard Cite

Variable Vocal Cord Dysfunction Presenting as Wheezing and Exercise-Induced Asthma

Cited by 50 publications

References 7 publications

Exercise-induced laryngeal obstructions: prevalence and symptoms in the general public

Exercise-induced laryngeal obstructions: prevalence and symptoms in the general public

Paradoxical Vocal Cord Dysfunction in Juveniles

Inspiratory muscle strength training with behavioral therapy in a case of a rower with presumed exercise-induced paradoxical vocal-fold dysfunction

Contact Info

Product

Resources

About