2022
DOI: 10.1186/s13550-022-00900-3
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Abstract: Background Although most guidelines suggest performing a positron emission tomography/computed tomography (PET/CT) with somatostatin receptor (SSTR) ligands for staging of pulmonary carcinoid tumours (PC), only a limited number of studies have evaluated the role of this imaging tool in this specific patient population. The preoperative differentiation between typical carcinoid (TC) and atypical carcinoid (AC) and the extent of dissemination (N/M status) are crucial factors for treatment allocat… Show more

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Cited by 9 publications
(3 citation statements)
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“…There was no agreement on the use of FDG in cases of atypical lung carcinoids. This result was unexpected (especially in the staging and before‐surgery settings) based on the observed high glucose metabolism of these neoplasms 25 and on the absence or low levels of SST expression in half of patients with atypical carcinoids 26 . In a recent report including 252 lung NEN, comprising 29 atypical and 61 large cell forms (LCNEC), FDG was performed before surgery in 90% (26/29) of atypical lung carcinoids and in 77% (47/61) of LCNEC, being positive in almost all cases (atypical lung carcinoid: 96%, 25/26; LCNEC: 100%, 47/47) 27 .…”
Section: Discussionmentioning
confidence: 96%
“…There was no agreement on the use of FDG in cases of atypical lung carcinoids. This result was unexpected (especially in the staging and before‐surgery settings) based on the observed high glucose metabolism of these neoplasms 25 and on the absence or low levels of SST expression in half of patients with atypical carcinoids 26 . In a recent report including 252 lung NEN, comprising 29 atypical and 61 large cell forms (LCNEC), FDG was performed before surgery in 90% (26/29) of atypical lung carcinoids and in 77% (47/61) of LCNEC, being positive in almost all cases (atypical lung carcinoid: 96%, 25/26; LCNEC: 100%, 47/47) 27 .…”
Section: Discussionmentioning
confidence: 96%
“…The use of gallium-68 ( 68 Ga) has increased over the last few years [ 9 ], especially for the diagnosis of prostate cancer (PCa) with [ 68 Ga]Ga-PSMA [ 10 ], and neuroendocrine tumours (NET) with [ 68 Ga]Ga-DOTA-TOC [ 11 , 12 ]. However, these are still novel radiopharmaceuticals, so there is a paucity of studies addressing occupational dosimetry from exposure to 68 Ga-based peptides [ 13 ].…”
Section: Introductionmentioning
confidence: 99%
“…Although tumors that cause TIO can occur in any part of the body, occurrence in the lung was only very rarely reported 3–5 . Because many other etiologies, not only neuroendocrine tumors/carcinoid but also metastatic pheochromocytoma, 16 pulmonary sclerosing pneumocytoma, 17 pulmonary lymphoepithelioma-like carcinoma, 18 harmatoma, 19 and inflammation can also show increased DOTATATE activity in the lungs 20,21 . Caution is warranted in the interpretation of mildly increased DOTATATE activity in the lungs.…”
mentioning
confidence: 99%