Validity of the EQ-5D in assessing and valuing health status in patients with schizophrenic, schizotypal or delusional disorders

Abstract

The EQ-5D showed a moderate ceiling effect and seems to be reasonably valid in this patient group.

A systematic review, psychometric analysis and qualitative assessment of generic preference-based measures of health in mental health populations and the estimation of mapping functions from widely used specific measures

“…Participants included males and females with a mean age of participants with a schizophrenia spectrum disorder, reported in 21 of the 33 studies, ranging between 20.3 and 57.9 years. 48,68,[70][71][72][73][75][76][77][78][79][80]82,84,86,[88][89][90][91]94,95 All studies obtained HRQoL information from patients; seven of these studies compared patient HRQoL values with published general population 'normative' values, [70][71][72][73][74][75][76] three compared HRQoL values with normal comparison participants that were recruited to the study [77][78][79] and two used 'norms' from healthy participants who had taken part in large surveys.…”

“…health-state utility values. 48,90 There was some evidence that associations with measures of depression were comparatively stronger than those with symptom measures of schizophrenia [e.g. the Positive and Negative Syndrome Scale (PANSS)].…”

“…the Positive and Negative Syndrome Scale (PANSS)]. 71,[88][89][90] When testing associations between measures for convergent validity (or change scores in responsiveness), there are reasons to predict that stronger and more consistent correlations might exist between generic HRQoL measures and functioning [e.g. Global Assessment of Functioning (GAF), Social and Occupational Functioning Assessment Scale (SOFAS)] or mental health/schizophrenia-specific HRQoL [e.g.…”

Health-related quality of life and metabolic risk in patients with psychosis

“…The generic health-related quality of life assessment instrument EQ5D has been used in population surveys in many countries (Burstrom et al, 2001;Kind et al, 1998) , and has also been proved valid in patients with schizophrenia (Bobes et al, 2005;Konig et al, 2007). The EQ5D generates a health profile together with a single index score for HRQoL (Konig et al, 2007) and can detect differences in quality of life among patients with different disease severity (Bobes et al, 2005).…”

“…The EQ5D generates a health profile together with a single index score for HRQoL (Konig et al, 2007) and can detect differences in quality of life among patients with different disease severity (Bobes et al, 2005).…”