Validation of a Piezoelectric Sensor Array-Based Device for Measurement of Carotid-Femoral Pulse Wave Velocity: The Philips Prototype

Abstract

Background: Multiple piezoelectric pressure mechanotransducers topologized into an array might improve efficiency and accuracy in collecting arterial pressure waveforms for measurement of pulse wave velocity (PWV). Objective: In the present study, we validated a piezoelectric sensor array-based prototype (Philips) against the validated and clinically widely used Complior device (Alam Medical). Methods: We recruited 33 subjects with a wide distribution of PWV. For the validation, PWV was measured sequentially with the Complior device (four times) and the Philips prototype (three times). With the 99 paired PWV values, we investigated the agreement between the Philips prototype and the Complior device using Pearson correlation analysis and Bland-Altman plot. We also performed analysis on the determinants and reproducibility of PWV measured with both devices. Results: The correlation coefficient for PWV measured with the two devices was 0.92 (p < 0.0001). Compared with the Complior device, the Philips prototype slightly overestimated PWV by 0.24 (± 2 standard deviations, ± 1.91) m/s, especially when PWV was high. The correlation coefficient between the difference and the average of the Philips and Complior measurements was 0.21 (p = 0.035). Nonetheless, they had similar determinants. Age, mean arterial pressure, and sex altogether explained 81.6 and 83.9% of the variance of PWV values measured with the Philips prototype and Complior device, respectively. When the two extremes of the three PWV values measured with the Philips prototype and the Complior device were investigated, the coefficients of variation were 8.26 and 3.26%, respectively. Conclusions: Compared with the Complior device, the Philips prototype had similar accuracy, determinants, and reproducibility in measuring PWV.

Intraoperative Beat-to-Beat Pulse Transit Time (PTT) Monitoring via Non-Invasive Piezoelectric/Piezocapacitive Peripheral Sensors Can Predict Changes in Invasively Acquired Blood Pressure in High-Risk Surgical Patients

“…Previous studies using piezo-based sensors have been able to reliably detect PWs in healthy volunteers [ 25 , 26 ], volunteers with arrythmias [ 23 ], and hypertensive patients [ 12 ]. In a recent study, the use of novel piezoelectric sensors resulted in a PW detection rate of 98% from the radial artery [ 27 ].…”

Assessment Parameters for Arrayed Pulse Wave Analysis and Application in Hypertensive Disorders

“…This pulse system was found to be effective compared with previous pulse acquisition platforms. Xu et al [ 21 ] confirmed that a piezoelectric sensor array-based device had similar accuracy and reproducibility for measuring the pulse wave velocity (PWV). Park et al [ 22 ] described a stretchable array of highly sensitive pressure sensors that consisted of polyaniline nanofibres and Au-coated polydimethylsiloxane micropillars that exhibited great potential in wearable devices.…”

WITHDRAWN: Assessment Parameters on Array Pulse Wave Analysis and Application in Hypertensive Disorders

“…This pulse system was demonstrated effectiveness than previous pulse acquisition platforms. Xu et al [19] validated that a piezoelectric sensor array-based device had similar accuracy and reproducibility in measuring pulse wave velocity (PWV). Park et al [20] reported a stretchable array of highly sensitive pressure sensors consisting of polyaniline nanofibers and au-coated polydimethylsiloxane micropillars, which showed great potential in wearable device.…”