Eur. J. Chem. volume 5, issue 3, P545-549 2014 DOI: 10.5155/eurjchem.5.3.545-549.1066
Ponnuveetil Gopi Sunitha, Kaliappan Ilango

KEYWORDSThe present work reports a reverse phase high performance liquid chromatography (RP-HPLC) method and high performance thin layer chromatography (HPTLC) method for the simultaneous determination of febuxostat and diclofenac sodium in pharmaceutical dosage form. HPLC was performed using a Thermo Hypersil C18 column (250 × 4.6 mm i.d., 5 μm particle size) using a mixture of methanol: KH2PO4 (0.02 M) (70:30, v:v) as mobile phase. Ultraviolet detection was carried out at 280 nm. The retention time of f…


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