Validação do método de extração e quantificação de 7-hidróxi- 4',6-dimetóxi-isoflavona em culturas de células em suspensão e calos de Dipteryx odorata

Fernandes, Rafael dos Santos; Lourenço, Miriam Verginia; Miranda, Carlos Eduardo Saraiva; França, Suzelei C.; Januário, Ana Helena

doi:10.1590/s0100-46702009000100002

Cited by 3 publications

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References 11 publications

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“…This compound was isolated by Jha et al (1980), from the desoxybenzoin obtained by condensation of phenols with derivatives of arylacetic acids or aliphatic acids. Fernandes et al (2009) isolated the isoflavone from suspension cell cultures and callus of Dipteryx odorata, popularly known as afrormosin or castanin. The chemical structure of the isoflavone is shown in Figure 1.…”

Section: Oxidation Inhibition With β-Carotene and Linoleic Acid (Bcb)mentioning

confidence: 99%

Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f

Pereira

Ferreira

et al. 2019

An. Acad. Bras. Ciênc.

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This study evaluated the antibacterial, antifungal, and antioxidant effect of 7-hydroxy-4',6dimethoxy-isoflavone and essential oil of Myroxylon peruiferum. The compound was isolated and its structure elucidated by NMR. The chemical composition of essential oil determined by gC-MS analysis. To evaluation of antimicrobial activity, the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were performed. In addition to analysis of antioxidant activity, DPPH radical scavenging tests, iron chelating assay (FIC), antioxidant reducing power assay (FRAP) and β-carotene bleaching assay (BCB) were performed. For the essential oil were identified 24 organized compounds having as main constituents; Germacrene D (17.2%), α-pinene (14.8%) and E-caryophyllene (10.8%). The results showed that isoflavone (2000 to 156 μg/mL) and essential oil (5.0 to 1.25%) present antibacterial and antifungal activity against Gram-positive bacteria and filamentous fungi. The isoflavone and the essential oil also presented antioxidant activity in all the tests, mainly on inhibition of the oxidation of β-carotene test concentrations ranging from 60 to 100%. In conclusion, isoflavone and essential oil from M. peruiferum present an antimicrobial alternative against gram-positive bacteria, especially of the genus Staphylococcus and dermatophyte fungi of the genus Trichophyton, as well as a natural compound antioxidant.

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Section: Oxidation Inhibition With β-Carotene and Linoleic Acid (Bcb)mentioning

confidence: 99%

Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f

Pereira

Ferreira

et al. 2019

An. Acad. Bras. Ciênc.

View full text Add to dashboard Buy / Rent full text

show abstract

Validação do método de extração e quantificação de 7-hidróxi- 4',6-dimetóxi-isoflavona em culturas de células em suspensão e calos de Dipteryx odorata

Cited by 3 publications

References 11 publications

Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f

Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f

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