Valacyclovir to Expedite the Clearance of Recurrent Herpes Gladiatorum

Abstract

A 7-day regimen of valacyclovir 500 mg BID will reduce the length of time until clinical clearance of an outbreak of recurrent HG. Its usage reduced duration of viral presence by 21%.

National Athletic Trainers' Association Position Statement: Skin Diseases

“…In an evidence-based study, Anderson 68 reported on the prophylactic use of valacyclovir and concluded that wrestlers with a history of HSV for more than 2 years were adequately treated with valacyclovir 500 mg/d, and those with a history of lesions for less than 2 years showed reductions in HSV infections with 1 g/d of valacyclovir. 145 Return to Competition. According to NCAA guidelines, 64 the athlete may not return to participation until he or she has received 5 days of oral antiviral therapy and all lesions have a dried, adherent crust (Table 3).…”

Effects of Anti Herpetic Drugs on Mice with Herpetic Epithelial Keratitis After Reactivation of Herpes Simplex Virus Type 1

“…Currently, the available medical treatments for HSV-1 and varicella zoster virus (VZV) infections include acyclovir (ACV), 14 famciclovir (FCV), 15,16 valacyclovir (VCV), 17 penciclovir (PCV), 18,19 and trifluorothymidine (TFT). 20 However, only 3% ACV eye ointment (ACV EO) and idoxuridine (IDU) eye drops are government-approved medications in Japan for patients with herpetic keratitis.…”

A-5021

“…C urrently available antiherpetic drugs are acyclovir (ACV), 1-3 trifluorothymidine (TFT), 4-6 famciclovir, 7-10 valacyclovir, 11,12 and penciclovir. [13][14][15][16] Because TFT is not approved for the treatment of herpes simplex keratitis in Japan, 3% ACV eye ointment (ACV EO) has been commonly used.…”