Vaginal delivery in SARS‐CoV‐2‐infected pregnant women in Northern Italy: a retrospective analysis

Ferrazzi, E.; Frigerio, Luigi; Savasi, Valeria; Vergani, Patrizia; Prefumo, Federico; Barresi, Santa; Bianchi, Stefano; Ciriello, Elena; Facchinetti, Fabio; Gervasi, Maria Teresa; Iurlaro, Enrico; Kustermann, Alessandra; Mangili, Giovanna; Mosca, Fabio; Patanè, Luisa; Spazzini, Donata; Spinillo, Arsenio; Trojano, Giuseppe; Vignali, Michele; Villa, Antonella; Zuccotti, Gian Vincenzo; Parazzini, Fabio; Cetin, Irene

doi:10.1111/1471-0528.16278

Cited by 260 publications

(416 citation statements)

References 12 publications

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“…28,30 Although some of the changes to care content and process are consistent with the updated guidelines on essential care provision, 40,71-73 other modifications diverge from available evidence, and could ultimately reverse achieved progress if proper action is not taken. These include the elimination of birth companions altogether, 73,74 reducing or banning visitors to maternity wards, performing caesarean section on all COVID-19 positive women, 74,75 augmenting labour or performing unindicated caesarean sections to gain control over timing of deliveries, separating newborns from COVID-19 positive mothers including not allowing breastfeeding, 76 and drastically reducing length-of-stay after facility birth with fewer home visit follow-ups. 47 These practices could deny women's access to quality, respectful intrapartum and postpartum care, and jeopardize their wellbeing and that of their babies.…”

Section: Responsementioning

confidence: 99%

Voices from the frontline: findings from a thematic analysis of a rapid online global survey of maternal and newborn health professionals facing the COVID-19 pandemic

Semaan

Audet

Huysmans

et al. 2020

Preprint

176

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ObjectiveTo prospectively document experiences of frontline maternal and newborn healthcare providers during the COVID-19 pandemic. DesignCross-sectional study via an online survey disseminated through professional networks and social media in 12 languages. We analysed responses using descriptive statistics and qualitative thematic analysis disaggregating by low-and middle-income countries (LMICs) and high-income countries (HICs).Setting 81 countries, between March 24 and April 10, 2020.Participants 714 maternal and newborn healthcare providers. Main outcome measuresPreparedness for and response to COVID-19, experiences of health workers providing care to women and newborns, and adaptations to 17 outpatient and inpatient care processes during the pandemic. ResultsOnly one third of respondents received training on COVID-19 from their health facility and nearly all searched for information themselves. Half of respondents in LMICs received updated guidelines for care provision compared with 82% in HICs. Overall, only 47% of participants in LMICs, and 69% in HICs felt mostly or completely knowledgeable in how to care for COVID-19 maternity patients. Facility-level responses to COVID-19 (signage, screening, testing, and isolation rooms) were more common in HICs than LMICs. Globally, 90% of respondents reported somewhat or substantially higher levels of stress. There was a widespread perception of reduced use of routine maternity care services, and of modification in care processes, some of which were not evidence-based. ConclusionsSubstantial knowledge gaps exist in guidance on management of maternity cases with or without COVID-19. Formal information sharing channels for providers must be established and mental health support provided. Surveys of maternity care providers can help track the situation, capture innovations, and support rapid development of effective responses. We would like to thank the study participants who took time to respond to this survey despite the difficult circumstances and increased workload. We acknowledge the Institutional

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Section: Responsementioning

confidence: 99%

Voices from the frontline: findings from a thematic analysis of a rapid online global survey of maternal and newborn health professionals facing the COVID-19 pandemic

Semaan

Audet

Huysmans

et al. 2020

Preprint

176

View full text Add to dashboard Cite

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“…The transmission was reported both in preterm 13,[22][23][24][25] and full-term born infants 23,26 and even where the infection prevention and control measures were in place 13,22,25 . Furthermore, the vertical transmission was reported regardless of the mode of delivery, vaginal 22,27 or cesarean route 13,[23][24][25][26] .…”

Section: Discussionmentioning

confidence: 99%

A systematic review of vertical transmission and antibodies against SARS-CoV-2 among infants born to mothers with COVID-19

Bwire¹,

Njiro²,

Mwakawanga³

et al. 2020

Preprint

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Amidst the Coronavirus Disease 2019 (COVID-19) pandemic, evidence on vertical transmission and natural passive immunity among the newborns exposed to COVID-19 is scanty and varies. This pose a challenge on preventive interventions for the newborns. We conducted a systematic review to first, determine the likelihood of vertical transmission among COVID-19 exposed infants and second, determine whether antibodies against Severe Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)/ COVID-19 virus exist among COVID-19 vertically exposed but negative infants. This review registered in PROSPERO searched evidence from PubMed/ MEDLINE and Google Scholar, among others. About 517 studies were retrieved, where only 33 articles (5.8%) qualified for final analysis. A total of 205 infants born to SARS-CoV-2 positive mothers were pooled from 33 eligible studies. Overall, 6.3% (13/205; 95%CI: 3.0%-9.7%) of the infants tested positive for COVID-19 virus at birth. Of 33 eligible studies, 6 studies (18.8%) reported about IgG/IgM against SARS-CoV-2. Anti-SARS-CoV-2 IgG/IgM were detected in 90% (10/11; 95%CI: 73.9%-107.9%) of infants who had no COVID-19 but vertically exposed. In conclusion, the current evidence revealed a low possibility of vertical transmission of COVID-19 while antibodies against SARS-CoV-2 were detected in most of the infants who had no COVID-19. Further studies on perinatal outcomes and the magnitude of natural passive immunity in infants born to mothers with COVID-19 are warranted.

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“…Although direct evidence of viral positive reverse transcriptase-polymerase chain reaction (RT-PCR) were mostly negative in large majority of reported studies, the paucity of published data is limited with small cohort numbers , limited sensitivity and speci city of swab tests and rapid evolution of COVID-19 infection. [33][34][35][36]. Hence, more data is needed about the risk of vertical transmission before de nitive conclusions can be made.…”

Section: Discussionmentioning

confidence: 99%

Attitude and perceptions towards COVID-19 among pregnant women in Singapore: A cross-sectional survey

Lee

Loy

Yang

et al. 2020

Preprint

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Background COVID-19 may predispose pregnant women to higher risks of severe disease and poorer neonatal outcome. Psychological sequalae of this pandemic may pose a greater conundrum than its clinical aspects. It is currently unknown that how pregnant women cope with this global pandemic and its ramifications. The aims of the study are to understand the attitude and perceptions of non-infected pregnant women towards the COVID-19 outbreak in Singapore. Methods An online cross-sectional survey of COVID-19 awareness among pregnant women attending antenatal clinics in Singapore was conducted. An internet link was provided to complete an online electronic survey on Google platform using a quick response (QR) code on mobile devices. The online survey consists of 34 questions that were categorized into 4 main sections, namely 1) social demographics 2) attitude on safe distancing measures 3) precaution practices and 4) perceptions of COVID-19. Results A total of 167 survey responses were obtained over eight weeks from April to June 2020. The majority of women were aged ≤35 years (76%, n=127), were of Chinese ethnicity (55%, n=91), attained tertiary education (62%, n=104) and were not working as frontline staff (70%). Using multiple linear regression models, Malay ethnicity (vs. Chinese, β 0.24; 95% CI 0.04, 0.44) was associated with higher frequency of practicing social distancing. Malay women (β 0.48; 95% CI 0.16, 0.80) and those who worked as frontline staff (β 0.28; 95% CI 0.01, 0.56) sanitized their hands at higher frequencies. Age of ≥36 years (vs. ≤30 years, β 0.24; 95% CI 0.01, 0.46), Malay (vs. Chinese, β 0.27; 95% CI 0.06, 0.48) and Indian ethnicity (vs. Chinese, β 0.41; 95% CI 0.02, 0.80), and attendance at high-risk clinic (vs. general clinic, β 0.20; 95% CI 0.01, 0.39) were associated with higher frequency of staying-at-home.Conclusion It is important for clinicians to render appropriate counselling and focused clarification on the effect of COVID-19 among pregnant women for psychological support and mental wellbeing.

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Vaginal delivery in SARS‐CoV‐2‐infected pregnant women in Northern Italy: a retrospective analysis

Cited by 260 publications

References 12 publications

Voices from the frontline: findings from a thematic analysis of a rapid online global survey of maternal and newborn health professionals facing the COVID-19 pandemic

Voices from the frontline: findings from a thematic analysis of a rapid online global survey of maternal and newborn health professionals facing the COVID-19 pandemic

A systematic review of vertical transmission and antibodies against SARS-CoV-2 among infants born to mothers with COVID-19

Attitude and perceptions towards COVID-19 among pregnant women in Singapore: A cross-sectional survey

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Vaginal delivery in SARS‐CoV‐2‐infected pregnant women in Northern Italy: a retrospective analysis

Cited by 260 publications

References 12 publications

Voices from the frontline: findings from a thematic analysis of a rapid online global survey of maternal and newborn health professionals facing the COVID-19 pandemic

Voices from the frontline: findings from a thematic analysis of a rapid online global survey of maternal and newborn health professionals facing the COVID-19 pandemic

A systematic review of vertical transmission and antibodies against SARS-CoV-2 among infants born to mothers with COVID-19

Attitude and perceptions towards&nbsp;COVID-19 among pregnant women in Singapore: A cross-sectional survey

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Attitude and perceptions towards COVID-19 among pregnant women in Singapore: A cross-sectional survey