Vacina antivariólica: ciência, técnica e o poder dos homens, 1808-1920

Verani, José Roberto

doi:10.1590/s0102-311x2011000200022

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“… Proposição da implantação do Programa Nacional de Serviços Básicos de Saúde (Prev-Saúde), tendo como foco da atenção os cuidados básicos de saúde e a integração do MS com o MPAS e a articulação dos serviços, envolvendo instituições do setor público e privado 97. 1980 Declaração da erradicação mundial da varíola, após longo processo para certificar a interrupção da transmissão humana do variola virus de pessoa a pessoa 98.  Estabelecimento da não obrigatoriedade da vacinação contra a varíola no País 99.…”

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Comorbidities and in-hospital death of viral pneumonia adults admitted to SUS (2002–2015)

et al. 2021

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OBJECTIVE To identify demographic and clinical characteristics of adult patients hospitalized in the Brazilian Unified Health System (SUS) due to viral pneumonia and investigate the association between some comorbidities and death during hospitalization. METHODS This retrospective cohort study was conducted with secondary data of adults admitted to SUS due to viral pneumonia between 2002 and 2015. Patient profile was characterized based on demographic and clinical variables. The association between the ten Elixhauser comorbidities and in-hospital death was investigated using Poisson regression models with robust standard errors. Results were quantified as incidence rate ratio (IRR) with 95% confidence intervals (CI), and we built five models using successive inclusion of variables blocks. RESULTS Hospital admissions for viral pneumonias decreased throughout the study period, and it was observed that 5.8% of hospitalized patients had an in-hospital death. We observed significant differences in demographic and clinical characteristics by comparing individuals who died during hospitalization with those who did not, with the occurrence of one or more comorbidities being more expressive among patients who died. Although not considered risk factors for in-hospital death, chronic pulmonary disease and congestive heart failure were the most common comorbidities. Conversely, IRR for in-hospital death increased with other neurological disorders, diabetes, cancer, obesity, and especially with HIV/AIDS. CONCLUSIONS Individuals presenting with pulmonary and cardiovascular diseases require proper attention during hospitalization, as well as those with other neurological diseases, diabetes, cancer, obesity, and especially HIV/AIDS. Understanding the influence of chronic diseases on viral infections may support the healthcare system in achieving better outcomes.

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