Uvulopalatopharyngoplasty in 158 OSAS patients failing non-surgical treatment

Abstract

In all, 76% of the patients underwent sleep recordings preoperatively and postoperatively. The oxygen desaturation index (ODI(4)) decreased from median 23 (range 6-100) to 8 (range 0-60), p<0.001. Criteria of success (>50% reduction and ODI<20), was 64%. The ESS value decreased from median 12 (range 0-21) to 6 (0-22), p<0.001. In all, 88% of the patients were satisfied. Four of 158 patients (2.5%) had serious postoperative complications. There was neither sequel of complications nor mortality.

Simultaneous Tonsillectomy and Nasal Surgery in Adult Obstructive Sleep Apnea

“…[10][11][12] All subjects, with 1 exception, were downstaged to mild residual OSA, allowing for the clinical cessation of nocturnal CPAP. The improvement in the RDI may lead to reduced long-term sequelae and may provide for increased adherence with CPAP for the subjects requiring intervention for residual disease.…”

SKUP3RCT; continuous study: Changes in sleepiness and quality of life after modified UPPP

“…In our RCT, the median ESS score was halved from 12 to 6 in the intervention group, and this result is identical to those from a 1-year follow-up of 158 OSAS patients in a study from our group. 21 Furthermore, in our 15-year follow-up of another study of 50 OSAS patients, the median ESS score after UPPP was 6. 22 These findings are also similar to those in other studies investigating the effects of UPPP; for example, the one by Yaremchuk et al 23 and the multicenter study by Weaver et al 24 The fact that this RCT (level 1 evidence) found similar outcomes suggests that the results from previous case series are reasonably accurate, because this RCT validates the results of these previous case series studies.…”

“…The median ESS score had significantly decreased from 12 (range 8-21) to 6 (2-16) (P < 0.001) in the intervention group, a mean reduction of 5.7 (3.9). The corresponding change for the control group was nonsignificant, from a median of 13 (8-18) to 12 (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21), with a significant difference between the groups (P < 0.001) (Fig. 2).…”

“…The sample size calculation was based on the night-to-night variability of the oxygen desaturation index values in patients with OSAS, 20 and also from one of our previous studies on patients with OSAS undergoing UPPP. 21…”

Comparison of the effects of dexmedetomidine-ketamine and sevoflurane-sufentanil anesthesia in children with obstructive sleep apnea after uvulopalatopharyngoplasty: An observational study

“…Uvulopalatopharyngoplasty (UPPP), one of the most common surgical procedures for the treatment of OSAS, was demonstrated to be effective and safe. [2] However, the postoperative period after UPPP is often challenging as children with OSA undergoing UPPP are at significant risk of respiratory and cardiovascular complications. [3] They also need to be adminstered effective and safe perioperative analgesia with effective prevention of emergence agitation (EA).…”