Uveitis-like syndrome and iris transillumination after the use of oral moxifloxacin

Willermain, François; Deflorenne, C; Bouffioux, Christophe; Janssens, Xavier; Koch, Philippe; Caspers, Laure

doi:10.1038/eye.2010.19

Cited by 31 publications

(30 citation statements)

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“…However, diffuse iris transillumination and mydriasis developed. Similarly, Willermain et al 6 reported a case with bilateral symptomatic acute iris transillumination, pigment dispersion, and severe IOP increase following oral moxifloxacin use. Heavy pigment deposition and iris concavity also developed in that case.…”

Section: Discussionmentioning

confidence: 95%

“…[1][2][3] A few studies have reported other diseases presenting with pigment dispersion and iris transillumination defects. [4][5][6] However, no previous report shows active discharge from an iris epithelial cyst. We describe a case with unusual clinical characteristics including iris cyst formation and pigment showering that led to iris transillumination as well as pupil distortion.…”

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confidence: 99%

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Recurrent iris cyst discharge

Altan-Yaycıoğlu¹,

Canan²,

Akova³

2012

Journal of Cataract and Refractive Surgery

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A 23-year-old woman with the diagnosis of anterior uveitis in the left eye was referred to our clinic. Circumferential midzonal iris epithelial cysts were observed in the right eye and corneal endothelial pigment precipitates and diffuse pigment discharge in the anterior chamber of the left eye. Topical prednisolone acetate was prescribed. After 2 days, hyperemia and pain decreased in the left eye and started in the right eye. During the following 3 months, the patient experienced 3 similar episodes, which resulted in diffuse pigment deposition in the anterior chamber angles. Intraocular pressure (IOP) elevation was observed after 1 week and 3 weeks in the left eye and right eye, respectively. Topical antiglaucomatous medication was prescribed. Nine months after the last episode, the uncorrected distance visual acuity was 20/20 and the IOP was 15 mm Hg bilaterally. The iris showed diffuse transillumination, and the pupils were unresponsive to light.

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Section: Discussionmentioning

confidence: 95%

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confidence: 99%

Recurrent iris cyst discharge

Altan-Yaycıoğlu¹,

Canan²,

Akova³

2012

Journal of Cataract and Refractive Surgery

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“…Previous cases have been reported in Turkey (5,6) (51 cases), Netherlands (3,7) (4 cases), Belgium (3,4,6) (4 cases), Spain (2) (one case) and France (8) (one case). We describe the first reported case in the Southern Hemisphere.…”

Section: Introductionmentioning

confidence: 99%

“…Patients typically present with acute and usually severe photophobia, red eye, and ocular discomfort or pain, which sometimes simulates acute bilateral iridocyclitis. Cases often occur after a flulike illness or upper respiratory tract infection, some of them after the use of oral moxifloxacin (2)(3)(4) . Middle-aged women are most commonly affected.…”

Section: Introductionmentioning

confidence: 99%

Bilateral acute depigmentation of the iris (BADI): first reported case in Brazil

Maestrini¹,

Maestrini²,

Machado³

et al. 2013

Arq. Bras. Oftalmol.

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“…[40][41][42][43][44][45][46][47] While the clinical characteristics of the uveitis induced by TNFα antagonists vary from patient to patient, suggestive clinical findings appear to include the presence of granulomatous features and the development of periphlebitisfeatures often observed in ocular sarcoidosis. As with other agents known to promote intraocular inflammation, TNFα-associated uveitis typically resolves …”

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confidence: 99%