Uveitis in northern Portugal

Abstract

During the past four years 450 patients (247 female - mean age 36 years and 203 male - mean age 34 years) with intraocular inflammation were evaluated using standard diagnostic criteria, to establish a uveitis survey profile. Patients were divided into four anatomic groups: anterior uveitis (270 cases = 60%), posterior uveitis (108 cases = 24%), panuveitis (54 cases = 12%) and intermediate uveitis (18 cases = 4%). A probable aetiological diagnosis was made in 232 cases (51.5%). Rheumatic diseases were diagnosed most commonly (55 cases = 12.2%), mainly ankylosing spondylitis, as is true for other European countries. Ocular toxoplasmosis was a frequent cause of uveitis, as in Brazil and West Africa, thus requiring a prompt diagnosis and treatment. Behçet's syndrome was associated with HLA B5 (65%) as in Japanese and Mediterranean populations. In our area AIDS retinitis is becoming an important differential diagnosis.

Fluorescein angiographic findings and clinical features in Fuchs’ uveitis

“…In the 15th edition of his textbook Fuchs described the main features that are crucial in diagnosing Fuchs' uveitis: these include fine retrodescemetic keratic precipitates (KPs), vitreous infiltration, absence of iris inflammation, atrophic iris changes, lens opacification and good tolerance to surgery [2]. Fuchs' uveitis is seen around the world [3][4][5][6] and its frequency in uveitis studies varies from 2% in Japan [7] and Portugal [8] to 8.32% in Italy [9]. Its aetiology is unknown but the main hypothesis is that an infectious triggering factor, possibly rubella virus and/or other viruses [10][11][12], is at the origin of an autoimmune disease in genetically susceptible patients [13][14][15].…”

Role and Regulation of IL-8 and MCP-1 in LPS-induced Uveitis in Rabbits

“…Whitcup and Palestine, 1996), the most common form of human intraocular inflammatory diseases (Henderly et al, 1987 ;Palmares, Coutinho and Castro-Correia, 1990 ;Perkins and Folk, 1984 ;Rosenbaum, 1989 ;Rothova et al, 1992 ;Smit, Baarsma and de Vries, 1993). Accumulated evidence suggests that IL-8 and MCP-1 may mediate ocular inflammatory responses.…”

Caracterización de las uveítis diagnosticadas en un centro de referencia del área de Barcelona

“…En nuestra serie, la media de edad fue de 46 añ os, superior a la descrita previamente en nuestro medio 7,8 y en países de nuestro entorno [17][18][19] . Esta diferencia es fá cilmente explicable, ya que en nuestro centro só lo se atienden pacientes pediá tricos con uveítis de forma excepcional, siendo referidos a otro servicio especializado en oftalmología pediá trica.…”

“…Las UI fueron el tipo anató mico con presentació n significativamente má s joven (p = 0,008). La distribució n por sexos de nuestros pacientes, con un ligero predominio femenino (58%), es superponible al de otras series de nuestro entorno 8,17,18,21 . Un 14% de los casos ocurrieron en pacientes extranjeros.…”