Uveitis: a global perspective

Chang, John H; Wakefield, Denis

doi:10.1076/ocii.10.4.263.15592

Cited by 296 publications

(251 citation statements)

References 31 publications

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“…[30][31][32] Data from referral centres revealed that anterior uveitis was the most common form of uveitis (27.8-63%), followed by posterior (9.3-38%) or panuveitis (7-38%), and intermediate uveitis (4-17%). 33 Chronic uveitis were more common than acute uveitis, and nongranulomatous uveitis occurred more frequently than did granulomatous uveitis. Findings from community-based studies showed a significantly higher rate of anterior uveitis and lower rate of other forms of uveitis.…”

Section: Discussionmentioning

confidence: 94%

“…The reported frequency of a systemic 33 There was however a large discrepancy between different studies in the proportion of idiopathic cases among other forms of uveitis. 33 The most common specific diagnoses in our uveitis population were Behçet's disease, herpetic infection, toxoplasmosis, and VKH disease.…”

Section: Discussionmentioning

confidence: 98%

“…The rate of herpetic uveitis in our patients (11.9%) is high compared to those found in previous reports. 7,9,10,13,17,33 It is unclear if this discrepancy is due to differences in the circulating virus's virulence, background immunity, or prevalence of other predisposing genetic or acquired conditions in the affected populations. Laboratory tests on aqueous humour aspirates, analysing antibodies against viruses HSV or VZV, or detecting viral particles using PCR, might be useful in diagnosing atypical presentations of HSV and VZV infections.…”

Section: Discussionmentioning

confidence: 99%

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Pattern of uveitis in a referral centre in Tunisia, North Africa

Khairallah

Yahia

Ladjimi

et al. 2006

Eye

160

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

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Pattern of uveitis in a referral centre in Tunisia, North Africa

Khairallah

Yahia

Ladjimi

et al. 2006

Eye

160

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“…2005); hereafter, non‐infectious intermediate, posterior and panuveitis will be referred to collectively as NIIPPU. Compared with anterior disease, which is the most common non‐infectious form (Chang & Wakefield 2002; Gritz & Wong 2004; Acharya et al. 2013; Miserocchi et al.…”

Section: Introductionmentioning

confidence: 99%

“…2013; Miserocchi et al. 2013), NIIPPU is more often associated with a poorer prognosis (Chang & Wakefield 2002; Barisani‐Asenbauer et al. 2012).…”

Section: Introductionmentioning

confidence: 99%

Direct and indirect resource use, healthcare costs and work force absence in patients with non‐infectious intermediate, posterior or panuveitis

Thorne

Skup

Tundia

et al. 2016

Acta Ophthalmologica

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PurposeTo ascertain resource use, costs and risk of workforce absence in non‐infectious uveitis cases versus matched controls.MethodsIn a retrospective claims analysis of employees in the United States, prevalent (N = 705) and incident (N = 776) cases 18–64 years old with ≥2 diagnoses of non‐infectious intermediate, posterior or panuveitis were matched 1:1 to controls without uveitis. Persistent prevalent cases (treated for ≥90 days, N = 112) also were analysed. Outcomes were annual direct resource use and costs associated with inpatient stays; emergency department, outpatient and ophthalmologist/optometrist visits; and prescription drugs. Indirect resource use and costs associated with work loss from disability and medically related absenteeism also were compared. Multivariate regression assessed cost differences between cases and controls.ResultsCases had significantly (p < 0.05) more medical resource use versus controls including 0.4 versus 0.2 emergency visits and 16.5 versus 7.6 outpatient/other visits. Cases used more prescription drugs (7.8 versus 4.1) and had more disability days (10.3 versus 4.6), medically related absenteeism days (8.5 versus 3.8), and work loss days (18.7 versus 8.4) than controls (all p < 0.05). Total direct ($12 940 versus $3730) and indirect ($3144 versus $1378) costs were higher in cases than controls (all p < 0.05). Results for persistent cases suggested greater utilization and associated cost and work loss burden. Compared with controls, cases had significantly greater risks of workforce absence, leave of absence and long‐term disability (all p < 0.05).ConclusionNon‐infectious intermediate, posterior or panuveitis, particularly persistent disease, is associated with substantial medical and work loss costs suggesting an unmet need for more effective treatments.

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