Uveal Pigment

The Ruptured Globe, Sympathetic Ophthalmia, and the 14-Day Rule

“…Several authors reported cases of suspected SO following enucleation of the exciting eye even when the injured was excised as early as 48 h post-injury. 136,144–150 More recently, Bellan 3 described a case of SO despite having the ruptured globe removed 5 days postinjury and challenged the concept that enucleation within 14 days eliminates the risk of SO. He also made some calculations based on 10,000 theoretical patients with penetrating ocular injury.…”

“…In a review of 136 case studies (from Fuchs, Joy, Verhoeff, and Woods) there was only one instance of SO developing when the exciting eye had been enucleated within 2 weeks after injury. 136,146–149…”

“…It may also be a low estimate since the worst reported responses to treatment were used for all calculations, and there was an assumption that enucleation within 2 weeks was completely protective of SO which it is not. 3,136,144–152 Bellan 3 suggested prophylactic enucleation of an unsalvageable eye following perforating injury should not be mandatory. In another review by Brackup et al 153 50 patients, with severe globe rupture and visual acuities of less than or equal to hand motion did not have the injured eye removed within 2 weeks to prevent SO.…”

The Ruptured Globe, Sympathetic Ophthalmia, and the 14-Day Rule

“…Several authors reported cases of suspected SO following enucleation of the exciting eye even when the injured was excised as early as 48 h post-injury. 136,144–150 More recently, Bellan 3 described a case of SO despite having the ruptured globe removed 5 days postinjury and challenged the concept that enucleation within 14 days eliminates the risk of SO. He also made some calculations based on 10,000 theoretical patients with penetrating ocular injury.…”

“…In a review of 136 case studies (from Fuchs, Joy, Verhoeff, and Woods) there was only one instance of SO developing when the exciting eye had been enucleated within 2 weeks after injury. 136,146–149…”

“…It may also be a low estimate since the worst reported responses to treatment were used for all calculations, and there was an assumption that enucleation within 2 weeks was completely protective of SO which it is not. 3,136,144–152 Bellan 3 suggested prophylactic enucleation of an unsalvageable eye following perforating injury should not be mandatory. In another review by Brackup et al 153 50 patients, with severe globe rupture and visual acuities of less than or equal to hand motion did not have the injured eye removed within 2 weeks to prevent SO.…”

The Ruptured Globe, Sympathetic Ophthalmia, and the 14-Day Rule

“…Several authors reported cases of suspected SO following enucleation of the exciting eye even when the injured was excised as early as 48 h post-injury. 136,144–150 More recently, Bellan 3 described a case of SO despite having the ruptured globe removed 5 days postinjury and challenged the concept that enucleation within 14 days eliminates the risk of SO. He also made some calculations based on 10,000 theoretical patients with penetrating ocular injury.…”

“…In a review of 136 case studies (from Fuchs, Joy, Verhoeff, and Woods) there was only one instance of SO developing when the exciting eye had been enucleated within 2 weeks after injury. 136,146–149…”

“…It may also be a low estimate since the worst reported responses to treatment were used for all calculations, and there was an assumption that enucleation within 2 weeks was completely protective of SO which it is not. 3,136,144–152 Bellan 3 suggested prophylactic enucleation of an unsalvageable eye following perforating injury should not be mandatory. In another review by Brackup et al 153 50 patients, with severe globe rupture and visual acuities of less than or equal to hand motion did not have the injured eye removed within 2 weeks to prevent SO.…”

The Ruptured Globe, Sympathetic Ophthalmia, and the 14-Day Rule

“…Several authors reported cases of suspected SO following enucleation of the exciting eye even when the injured was excised as early as 48 h post-injury. 136,144–150 More recently, Bellan 3 described a case of SO despite having the ruptured globe removed 5 days postinjury and challenged the concept that enucleation within 14 days eliminates the risk of SO. He also made some calculations based on 10,000 theoretical patients with penetrating ocular injury.…”

“…In a review of 136 case studies (from Fuchs, Joy, Verhoeff, and Woods) there was only one instance of SO developing when the exciting eye had been enucleated within 2 weeks after injury. 136,146–149…”

“…It may also be a low estimate since the worst reported responses to treatment were used for all calculations, and there was an assumption that enucleation within 2 weeks was completely protective of SO which it is not. 3,136,144–152 Bellan 3 suggested prophylactic enucleation of an unsalvageable eye following perforating injury should not be mandatory. In another review by Brackup et al 153 50 patients, with severe globe rupture and visual acuities of less than or equal to hand motion did not have the injured eye removed within 2 weeks to prevent SO.…”