UVB and Vitamin D in Psoriasis

Osmancevic, Amra

doi:10.5772/25818

Cited by 4 publications

(8 citation statements)

References 140 publications

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“…At follow-up (2 months after treatment initiation), 71% of the children had vitamin D deficiency (<25 nmol/L), 29% had insufficient levels (25–50 nmol/L), whereas 0% had sufficient levels (<50 nmol/L). In the present study, only enzyme-inducing antiepileptic drugs were included, since those were included in the medical decision support system 9. A mean level of 59 nmol/L was found in the present study, which was slightly higher compared to Teagarden et al,35 and 33% had levels below 50 nmol/L = 20 ng/mL, which was slightly lesser than in Teagarden et al’s American study.…”

Section: Discussioncontrasting

confidence: 57%

“…Pharmaceutical substances listed as “drugs causing vitamin D deficiency”, in a commonly used medical decision-support website in Sweden, 9 was defined as “risk medications”. The following pharmaceutical substances were thus considered to be “risk medications” (ATC-code): prednisolone (H02AB06), prednisone (H02AB07), phenytoin (N03AB02), phenobarbital (N03AA02), carbamazepine (N03AF01), cholestyramine (C10AC01), colestipol (C10AC02), sevelamer (V03AE02), orlistat (A08AB01), and efavirenz (J05AG03).…”

Section: Methodsmentioning

confidence: 99%

“…Nordic medical guidelines, 8 as well as medical decision support systems, 9 , 10 emphasize the risk of vitamin D deficiency when prescribing these types of “risk medications” and suggest monitoring by testing for vitamin D and/or prescribing vitamin D supplements. These guidelines, published by national medical authorities, 8 as well as guidelines developed within health care, 9 together with the recommendations in decision support systems 10 all derive from peer-reviewed articles on “risk medication” as well as from international guidelines on management of vitamin D deficiency. 7 , 11 …”

Section: Introductionmentioning

confidence: 99%

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<p>Adherence to risk management guidelines for drugs which cause vitamin D deficiency – big data from the Swedish health system</p>

Nordqvist

Svensson

Brudin

et al. 2019

DHPS

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PurposeSeveral medications are known to cause vitamin D deficiency. The aim of this study is to describe vitamin D testing and supplementation in patients using these “risk medications”, thereby assessing adherence to medical guidelines.Patients and methodsA database with electronic health records for the population in a Swedish County (≈240,000 inhabitants) was screened for patients prescribed the pre-defined “risk medications” during a 2-year period (2014–2015). In total, 12,194 patients were prescribed “risk medications” pertaining to one of the three included pharmaceutical groups. Vitamin D testing and concomitant vitamin D supplementation, including differences between the included pharmaceutical groups, was explored by matching personal identification numbers.ResultsCorticosteroids were prescribed to 10,003 of the patients, antiepileptic drugs to 1,101, and drugs mainly reducing vitamin D uptake to 864. Two hundred twenty-six patients were prescribed >1 “risk medication”. Seven hundred eighty-seven patients (6.5%) had been tested during the 2-year period. There were no differences regarding testing frequency between groups. Concomitant supplements were prescribed to 3,911 patients (32.1%). It was more common to be prescribed supplements when treated with corticosteroids. Vitamin D supplementation was more common among tested patients in all three groups. Women were tested and supplemented to a higher extent. The mean vitamin D level was 69 nmol/L. Vitamin D deficiency was found in 24.1% of tested patients, while 41.3% had optimal levels. It was less common to be deficient and more common to have optimal levels among patients prescribed corticosteroids.ConclusionAdherence to medical guidelines comprising testing and supplementation of patients prescribed drugs causing vitamin D deficiency needs improvement in Sweden.

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Section: Discussioncontrasting

confidence: 57%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

<p>Adherence to risk management guidelines for drugs which cause vitamin D deficiency – big data from the Swedish health system</p>

Nordqvist

Svensson

Brudin

et al. 2019

DHPS

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“…Osmancevic [12] presents the application of the phototherapy technique for vitamin D injection in patients with psoriasis disease, which is the disease in which skin cells accumulate and form dry itchy scales and spots. Studies have shown that vitamin D inhibits inflammatory processes by suppressing the increased activity of immune cells taking part in the autoimmune reaction, and vitamin D injection has improved psoriasis in the patients being treated.…”

Section: Literature Reviewmentioning

confidence: 99%

“…The main source of vitamin D is ultraviolet rays, but absorption of this vitamin has to be done safely. Osmancevic [12] States that vitamin D3 is produced in the skin because of 7-dehydrocholesterol (7-DHC) ultraviolet radiation and D2 is produced by ultraviolet radiation from plant sterol ergosterol. This paper aims to implement an ultraviolet index monitoring system to assist in the prevention of diseases caused by solar ultraviolet radiation through warning messages with preventive measures for each change in the ultraviolet index over time.…”

Section: Introductionmentioning

confidence: 99%

IoT System for Ultraviolet Ray Index Monitoring

Almeida

Barreto²,

Souto³

et al. 2019

Int J Innov Educ Res

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Este artigo apresenta um sistema de monitoramento de índice ultravioleta usando aplicativos de IoT. O objetivo é auxiliar na prevenção de doenças causadas pela radiação solar ultravioleta por meio de mensagens de aviso com medidas preventivas a cada alteração no nível do índice ultravioleta ao longo do tempo. O monitoramento do índice de UV é de fundamental importância para a prevenção de várias doenças, como câncer de pele, doenças cardiovasculares, falta de cálcio e outras. O sistema apresentou bons resultados no monitoramento do índice UV, apresentando valores medidos dos índices UV de acordo com a radiação solar observada durante os experimentos, classificados de acordo com a Organização Mundial de Saúde (OMS).

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The Analysis of Serum Vitamin D (25[OH]D) Level in Psoriasis Patients Comparing with Control Subjects

Fernandes

Listiawan

Ervianti

et al. 2020

BIKK

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Background: Vitamin D has been shown to have an immunomodulatory effect, and previous studies have proven that vitamin D deficiency contributed to several autoimmune diseases, including psoriasis. Purpose: The purpose of this study was to determine serum vitamin D levels in psoriasis vulgaris patients and compare them with control subjects. Methods: The research samples were sixteen adults with psoriasis vulgaris and 16 control subjects. Blood samples were taken, and the serum 25 (OH) D levels were measured using the Chemiluminescent Microparticle Immunoassay method. Result: The mean serum vitamin D in psoriasis vulgaris patients and controls were 14.36 ± 6.36 and 19.92 ± 7.59 ng/mL, respectively. No psoriasis vulgaris were observed in patients with normal 25(OH)D levels, and only 3 control subjects with normal serum 25(OH)D levels. These results were not statistically significant (p = 0.09). Conclusion: Most patients with psoriasis vulgaris were observed having vitamin D deficiency. However, the prevalence of vitamin D deficiency in the control subjects was high as well. Therefore, there were no differences in serum 25(OH)D levels between psoriasis vulgaris and control patients.

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UVB and Vitamin D in Psoriasis

Cited by 4 publications

References 140 publications

<p>Adherence to risk management guidelines for drugs which cause vitamin D deficiency – big data from the Swedish health system</p>

<p>Adherence to risk management guidelines for drugs which cause vitamin D deficiency – big data from the Swedish health system</p>

IoT System for Ultraviolet Ray Index Monitoring

The Analysis of Serum Vitamin D (25[OH]D) Level in Psoriasis Patients Comparing with Control Subjects

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UVB and Vitamin D in Psoriasis

Cited by 4 publications

References 140 publications

<p>Adherence to risk management guidelines for drugs which cause vitamin D deficiency &ndash; big data from the Swedish health system</p>

<p>Adherence to risk management guidelines for drugs which cause vitamin D deficiency &ndash; big data from the Swedish health system</p>

IoT System for Ultraviolet Ray Index Monitoring

The Analysis of Serum Vitamin D (25[OH]D) Level in Psoriasis Patients Comparing with Control Subjects

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Product

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<p>Adherence to risk management guidelines for drugs which cause vitamin D deficiency – big data from the Swedish health system</p>

<p>Adherence to risk management guidelines for drugs which cause vitamin D deficiency – big data from the Swedish health system</p>