2021
DOI: 10.3389/fphys.2021.766382
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Abstract: Group B Streptococcus (GBS) infection during pregnancy is involved in maternal sepsis, chorioamnionitis, prematurity, fetal infection, neonatal sepsis, and neurodevelopmental alterations. The GBS-induced chorioamnionitis leads to a plethora of immune and trophoblast cells alterations that could influence endothelial cells to respond differently to angiogenic mediators and alter placental vascular structure and function in pregnant women. In this context, preventive measures are needed to reduce such dysfunctio… Show more

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Cited by 3 publications
(1 citation statement)
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References 68 publications
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“…Therefore, the Raman spectroscopy analysis performed in our study revealed molecular modifications compatible with an increased differentiation towards a more mesenchymal and migratory phenotype of the HTR‐8/SVneo cells expressing the N‐terminal deleted KLF6 protein. Nowadays, few Raman spectroscopy studies performed on trophoblast cells or tissue from human placentas have been reported [75–77], so this work provides additional evidence on the usefulness of this approach to analyze biological samples derived from human placenta.…”
Section: Discussionmentioning
confidence: 95%
“…Therefore, the Raman spectroscopy analysis performed in our study revealed molecular modifications compatible with an increased differentiation towards a more mesenchymal and migratory phenotype of the HTR‐8/SVneo cells expressing the N‐terminal deleted KLF6 protein. Nowadays, few Raman spectroscopy studies performed on trophoblast cells or tissue from human placentas have been reported [75–77], so this work provides additional evidence on the usefulness of this approach to analyze biological samples derived from human placenta.…”
Section: Discussionmentioning
confidence: 95%