Eur J Chem volume 10, issue 3, P239-243 2019 DOI: 10.5155/eurjchem.10.3.239-243.1786
Wafaa Abdou Zaghary, Ahmed Mostafa Abdalla, Emily Tawfik Hanna, Marwa Abdel Rahman Tohamy Zanoun
Abstract:

A simple and sensitive ultra-performance liquid chromatography with Tandem Mass Spectrometric detection (UPLC-MS/MS) method was developed and validated for the simultaneous quantitation of two food colouring matters, Curcumin (CUR) and Riboflavin (RIB). Chromatographic separation was done on Hypersil gold 50×2.1 mm (1.9 μm) column, with gradient programing of mobile phase starting with aqueous 0.1% formic acid and increasing the percentage of 0.1% formic acid in acetonitrile. The utilization of multiple re…

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