Utility of “<scp>MR</scp> myelography” in diagnosis of a presumed spinal subarachnoid diverticulum

Ito, Daisuke; Ishikawa, Chieko; Sekiguchi, N; Jeffery, Nick; Kitagawa, Masato

doi:10.1111/jsap.13208

Cited by 2 publications

(1 citation statement)

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“…For instance, the use of 3‐dimensional field echo steady state free procession (FE3D‐SSFP) images in conjunction with fast advanced spin echo (FASE) or half‐Fourier acquisition single‐shot turbo spin Echo (HASTE) images may help. 18 Computed tomography and myelography were not evaluated in our study, and it is unknown if other imaging modalities would have resulted in improved agreement scores. Without this information it would be difficult to recommend to owners that their dogs should undergo more invasive imaging after the initial MRI investigation.…”

Section: Discussionmentioning

confidence: 97%

Agreement and differentiation of intradural spinal cord lesions in dogs using magnetic resonance imaging

Krasnow¹,

Griffin

Levine

et al. 2021

Veterinary Internal Medicne

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Background Magnetic resonance imaging is the method of choice for diagnosing spinal cord neoplasia, but the accuracy of designating the relationship of a neoplasm to the meninges and agreement among observers is unknown. Objectives To determine agreement among observers and accuracy of diagnosis compared with histology when diagnosing lesion location based on relationship to the meninges. Animals Magnetic resonance images from 53 dogs with intradural extramedullary and intramedullary spinal neoplasms and 17 dogs with degenerative myelopathy. Methods Six observers were supplied with 2 sets of 35 images at different time points and asked to designate lesion location. Agreement in each set was analyzed using kappa ( κ ) statistics. We tabulated total correct allocations and calculated sensitivity, specificity, and likelihood ratios for location designation from images compared with known histologic location for lesions confined to 1 location only. Results Agreement in the first set of images was moderate ( κ = 0.51; 95% confidence interval [CI], 0.43‐0.58) and in the second, substantial ( κ = 0.69; 95% CI, 0.66‐0.79). In the accuracy study, 180 (75%) of the 240 diagnostic calls were correct. Sensitivity and specificity were moderate to high for all compartments, except poor sensitivity was found for intradural extramedullary lesions. Positive likelihood ratios were high for intradural extramedullary lesions and degenerative myelopathy. Conclusions and Clinical Importance Overall accuracy in diagnosis was reasonable, and positive diagnostic calls for intradural extramedullary lesions and negative calls for intramedullary lesions are likely to be helpful. Observers exhibited considerable disagreement in designation of lesions relationship to the meninges.

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Section: Discussionmentioning

confidence: 97%