Use of the Charlson Combined Comorbidity Index To Predict Postradiotherapy Quality of Life for Prostate Cancer Patients

Wahlgren, Thomas; Levitt, Seymour H.; Kowalski, Jan; Nilsson, Sten; Brandberg, Yvonne

doi:10.1016/j.ijrobp.2010.07.014

Cited by 15 publications

(13 citation statements)

References 25 publications

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“…The CCI was developed by Charlson et al [22], and it has been reported that CCI is strongly correlated with higher risk of surgery in NSCLC patients [12]. In the prostate cancer patients, it has been noted that CCI seems useful mainly in predicting long-term QOL and physical function scores [23]. In our study, it was proved that CCI is a predictor of postoperative M-QOL for NSCLC patients.…”

Section: Discussionsupporting

confidence: 58%

Perioperative Progress and Predictor of the Postoperative Mental Quality of Life for Lung Cancer Patients

2021

Br J Cancer Res

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Section: Discussionsupporting

confidence: 58%

Perioperative Progress and Predictor of the Postoperative Mental Quality of Life for Lung Cancer Patients

2021

Br J Cancer Res

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“…Examples of this are the studies in which the Charlson index was used to predict outcomes other than mortality (M. Charlson et al, 2014; Huntley et al, 2012; Radner et al, 2010; Wahlgren et al, 2011). At the same time, indices perform better in predicting the outcomes for which they were developed and many single indices do not seem adequate to predict multiple outcomes (Byles, D’Este, Parkinson, O’Connell, & Treloar, 2005).…”

Section: Measuring Multimorbidity In a Studymentioning

confidence: 99%

The measurement of multimorbidity.

Nicholson¹,

Almirall²,

Fortin

2019

Health Psychology

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Overview: The presence of multiple concurrent medical conditions (also known as multimorbidity) is now a common phenomenon, hence the importance of its measurement. Objective: The purpose of this paper is to review the multimorbidity measures that have been published in the literature to date and that are available for use in future research studies. Method: Two main groups of measures of multimorbidity could be distinguished. The first group of measures is constituted by a simple count from various lists of chronic conditions. The second group of measures introduces a weighting for included chronic conditions thus creating a “weighted index” of multimorbidity. These groups are not mutually exclusive as the list of medical conditions in some weighted indices can be used as a list of conditions without weighting. This article includes a review of the multimorbidity literature to date that has reported these groups of measurements, showing the variety of existing measurements and highlighting their differences to provide an overview of the possibilities that are available to a researcher intending to measure multimorbidity. Conclusion: Finally, we outline some guidelines for the choice of a measurement of multimorbidity for research studies. We hope that this review of the existing literature will help inform the careful use of these tools by researchers moving forward. In addition to this review, it is advised that readers attempt to keep updated on the ever-increasing multimorbidity literature.

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“…28 Despite this, another study of prostate cancer patients demonstrated a significant, yet relatively weak, association between CCI and long-term HRQoL. 29 A third study demonstrated a significant association between self-reported CCI and HRQoL, while CCI derived directly from medical records failed to predict HRQoL. 30 This makes sense because patients are probably more likely to report diseases that disturb their HRQoL.…”

Section: Discussionmentioning

confidence: 99%

Thoracotomy and VATS Surgery in Local Non–Small-Cell Lung Cancer: Differences in Long-Term Health-Related Quality Of Life

Rauma

Andersson

Robinson

et al. 2019

Clinical Lung Cancer

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Very long-term health-related quality of life (HRQoL) is an important end point in operated early stage non esmall-cell lung cancer with good prognosis. The results for very long-term HRQoL after minimally invasive video-assisted thoracoscopic surgery (VATS) has not been evaluated and compared to thoracotomy. Surprisingly, inferior overall HRQoL was evident for patients operated with VATS, independent of preoperative factors including age, comorbidities, and pulmonary function tests. Background: As a result of routine low-dose computed tomographic screening, lung cancer is more frequently diagnosed at earlier, operable stages of disease. In treating local nonesmall-cell lung cancer, video-assisted thoracoscopic surgery (VATS), a minimally invasive surgical approach, has replaced thoracotomy as the standard of care. While short-term quality-of-life outcomes favor the use of VATS, the impact of VATS on long-term health-related quality of life (HRQoL) is unknown. Patients and Methods: We studied patients who underwent lobectomy for the treatment of nonesmall-cell lung cancer from January 2006 to January 2013 at a single institution (n ¼ 456). Patients who underwent segmentectomy (n ¼ 27), who received neoadjuvant therapy (n ¼ 13), or who were found to have clinical stage > T2 or > N0 disease (n ¼ 45) were excluded from analysis. At time of HRQoL assessment, 199 patients were eligible for study and were mailed the generic HRQoL instrument 15D. Results: A total of 180 patients (90.5%) replied; 92 respondents underwent VATS while 88 underwent open thoracotomy. The VATS group more often had adenocarcinoma (P ¼ .006), and lymph node stations were sampled to a lesser extent (P ¼ .004); additionally, hospital length of stay was shorter among patients undergoing VATS (P ¼ .001). No other clinical or pathologic differences were observed between the 2 groups. Surprisingly, patients who underwent VATS scored significantly lower on HRQoL on the dimensions of breathing, speaking, usual activities, mental function, and vitality, and they reported a lower total 15D score, which reflects overall quality of life (P < .05). Conclusion: In contrast to earlier short-term reports, long-term quality-of-life measures are worse among patients who underwent VATS compared to thoracotomy.

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Use of the Charlson Combined Comorbidity Index To Predict Postradiotherapy Quality of Life for Prostate Cancer Patients

Cited by 15 publications

References 25 publications

Perioperative Progress and Predictor of the Postoperative Mental Quality of Life for Lung Cancer Patients

Perioperative Progress and Predictor of the Postoperative Mental Quality of Life for Lung Cancer Patients

The measurement of multimorbidity.

Thoracotomy and VATS Surgery in Local Non–Small-Cell Lung Cancer: Differences in Long-Term Health-Related Quality Of Life

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