2022
DOI: 10.1101/2022.06.03.494661
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Abstract: The primary goal in cell line development is to establish high-producer recombinant cell line(s) of single-cell origin. Traditionally, these cell lines are developed using limiting dilution cloning (LDC) method of single cell isolation, a rate-limiting, lengthy and labor-intensive process.   The Verified-In-Situ-Plate-Seeding (VIPS™) is an automated single-cell seeding and imaging equipment designed to accelerate cell line development workflow. In this study, VIPS™ was tested for efficiency and accuracy of sin… Show more

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