Use of Preoperative Magnetic Resonance Imaging for Invasive Lobular Cancer: Good, Better, but Maybe not the Best?

McGhan, Lee J.; Wasif, Nabil; Gray, Richard; Giurescu, Marina; Pizzitola, Victor; Lorans, Roxanne; Ocal, Idris Tolgay; Stucky, Chee Chee H.; Pockaj, Barbara A.

doi:10.1245/s10434-010-1266-y

Cited by 69 publications

(45 citation statements)

References 42 publications

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“…Limits within which measurements on MRI are considered concordant with measurements at pathology vary and range from 0 mm -20 mm [11,[24][25][26][27]. We used a limit of 10 mm to define concordance and Bland Altman plots to measure systematic and random differences.…”

Section: Discussionmentioning

confidence: 99%

Which factors influence MRI-pathology concordance of tumour size measurements in breast cancer?

et al. 2015

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Section: Discussionmentioning

confidence: 99%

Which factors influence MRI-pathology concordance of tumour size measurements in breast cancer?

et al. 2015

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“…Preoperative breast MRI has been found to be highly sensitive in detecting lesions not seen using mammography or ultrasound among patients with ILC [17]. However, only a few studies have examined the association between breast MRI and surgical outcomes in women with ILC [5, 18-20]. These studies were limited in that they were single institution studies [18-20] and an RCT from the United Kingdom[5] with a small number of ILC patients from settings with distinct surgical treatment patterns, health service resources, and insurance structures that may not be generalizable to the US elderly population.…”

Section: Introductionmentioning

confidence: 99%

Preoperative breast MRI and surgical outcomes in elderly women with invasive ductal and lobular carcinoma: a population-based study

Fortune-Greeley

Wheeler

Meyer

et al. 2013

Breast Cancer Res Treat

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Background Existing evidence suggests that preoperative breast magnetic resonance imaging (MRI) might not improve surgical outcomes in the general breast cancer population. To determine if patients differentially benefit from breast MRI, we examined surgical outcomes—initial mastectomy, reoperation, and final mastectomy rates—among patients grouped by histologic type. Methods We identified women diagnosed with early-stage breast cancer from 2004-2007 in the SEER-Medicare dataset. We classified patients as having invasive ductal carcinoma (IDC), invasive lobular carcinoma (ILC), mixed ductal/lobular carcinoma (IDLC) or other histologic type. Medicare claims were used to identify breast MRI and definitive surgeries during the initial surgical treatment episode. We used propensity score methods to account for the differential likelihood of exposure to MRI. Results Of the 20,333 patients who met our inclusion criteria for this study, 12.2% had a preoperative breast MRI. Patients with ILC as compared to other histologic groups were most likely to receive MRI (OR: 2.32; 95% CI: [2.02, 2.67]). In the propensity score adjusted analyses, breast MRI was associated with an increased likelihood of an initial mastectomy for all patients and among all histologic subgroups. Among patients with ILC, having a breast MRI was associated with lower odds of a reoperation (OR: 0.59; 95% CI [0.40, 0.86]), and an equal likelihood of a final mastectomy compared to similar patients without a breast MRI. Overall and among patients with IDC and IDLC, breast MRI was not significantly associated with a likelihood of a reoperation but was associated with greater odds of a final mastectomy. Conclusion Our study provides evidence in support of the targeted use of preoperative breast MRI among patients with ILC to improve surgical planning; it does not provide evidence for the routine use of breast MRI among all newly diagnosed breast cancer patients or among patients with IDC.

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“…This preoperative tool reduces the need for re-excision after BCS 22,23 . However, a recent meta-analysis has demonstrated that preoperative MRI potentially increases the mastectomy ratio 24 .…”

Section: Discussionmentioning

confidence: 99%

Volume of breast tissue excised during breast-conserving surgery in patients undergoing preoperative systemic therapy

Valejo¹,

Tiezzi²,

Mandarano³

et al. 2013

Rev. Bras. Ginecol. Obstet.

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Use of Preoperative Magnetic Resonance Imaging for Invasive Lobular Cancer: Good, Better, but Maybe not the Best?

Cited by 69 publications

References 42 publications

Which factors influence MRI-pathology concordance of tumour size measurements in breast cancer?

Which factors influence MRI-pathology concordance of tumour size measurements in breast cancer?

Preoperative breast MRI and surgical outcomes in elderly women with invasive ductal and lobular carcinoma: a population-based study

Volume of breast tissue excised during breast-conserving surgery in patients undergoing preoperative systemic therapy

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