Use of Cortoss™ as an Alternative Material in Calvarial Defects

Abstract

A clinical series of 13 patients who underwent cranioplasty using a new quick setting material, namely Cortoss, was done over 3-year period. Thus, the primary objective of this study is to evaluate the role of Cortoss in the treatment calvarial defects which were mainly due to trauma (4 patients), tumor or tumor-like lesions (5 patients), middle cerebral infarction (3 patients), and gun shot wound (1 patient). The surgical technique was found to be simple and effective. Long-term follow-up (mean 24.3 months) demonstrated satisfactory results in terms of surgical (functional) and cosmetic outcomes. None of the patients developed complications including infections, foreign body reactions or material leakage. The results led us to suggest that the use of Cortoss in the case of calvarial defects seems to be safe, effective, quick, and a feasible method for cranioplasty. We conclude that the mechanical, immunologic, and technical-grafting properties of Cortoss, together with its superior esthetic and psychological effects, probably will make it the best material for cranioplasty.

Long-term results following titanium cranioplasty of large skull defects

“…Bioactive materials are gaining greater importance and exhibit superior characteristics to classic allografts in biomechanical studies and small clinical short-term settings, 35,38 but they still have to stand the test of time. Osteoconductive bioresorbable materials, tissue engineering, 36,37,40,41 osteoinduction by growth factors, and gene therapy 12,17,31 are only recently gaining access in larger clinical settings.…”

“…9,18 Recently, bioactive composite materials consisting of acrylic resins gained access into calvarial reconstruction with good results. 38 Hydroxyapatite is probably the most frequently used ceramic and is increasingly used in reconstructive surgery. It is the principal component of bone, has the advantage of osteoconductivity, and allows osteointegration.…”

Efficacy and Versatility of the 3-D Titanium Mesh Implant in the Closure of Large Post-Craniectomy Osseous Defects, and its Therapeutic Role in Reversing the Syndrome of the Trephined: Clinical Study of a Case Series and Review of Literature

“…The Titanium mesh implant, by virtue of its excellent biocompatibility, corrosion resistance and ability to osseointegrate, makes it a very safe and reliable alternative to autografts and is sometimes even preferred over them [14]. Titanium mesh has been proved to have greater strength and provide a superior cranial contour restoration than the thin split thickness calvarial bone grafts [15]. Being a non-ferromagnetic metal, that is relatively radiolucent, Titanium induces no major artifacts, causes no significant scatter or image degradation on CT scans or on MRI and permits safe and accurate imaging of the brain in the long-term post operative follow up period [16].…”

Osteointegration of a Bisphenol-a-Glycidyl-Dimethacrylate Composite and Its Use in Anterior Skull Base Defects

“…[12][13][14][15] Their mechanical advantages, ease of application, and successful clinical results make them popular in operating theaters. 10,16 Biomechanical characteristics of bis-GMA-based materials in the living tissue were evaluated in only 1 animal study, which was conducted in long bones of rabbits and sheep. 15 However, these materials have not been studied in flat bones forming the anterior skull base.…”