Use of Betaxolol in the Reduction of Elevated Intraocular Pressure

A Synopsis of Recent Developments in Antiglaucoma Drugs

“…Metoprolol (3%) was as effective for five months as pilocarpine (2% and 4%) in glaucoma patients for without producing significant side effects or tachyphylaxis (104). A six week study of betaxolol (0.125%) in humans with ocular hypertension showed maintained reduction of IOP (105).…”

A Synopsis of Recent Developments in Antiglaucoma Drugs

“…Metoprolol (3%) was as effective for five months as pilocarpine (2% and 4%) in glaucoma patients for without producing significant side effects or tachyphylaxis (104). A six week study of betaxolol (0.125%) in humans with ocular hypertension showed maintained reduction of IOP (105).…”

Screening for Glaucoma in Adults

“…Across all key questions, 83 studies (reported in 96 publications, total 75 887 participants) were included (30 trials and 53 diagnostic accuracy studies) (Figure 2). Sixteen studies were carried forward from the 2013 reviews, and 67 studies were new.…”

“…Seventeen trials (n = 4665) evaluated medical treatments for OAG vs placebo or no treatment . Nine trials were in the 2013 review and 8 trials were added (eTable 9 in the Supplement). Two trials enrolled patients with untreated, newly diagnosed OAG, 3 trials enrolled mixed populations (OAG or ocular hypertension, and 12 trials enrolled patients with ocular hypertension.…”

“…Nine trials were in the 2013 review and 8 trials were added (eTable 9 in the Supplement). Two trials enrolled patients with untreated, newly diagnosed OAG, 3 trials enrolled mixed populations (OAG or ocular hypertension, and 12 trials enrolled patients with ocular hypertension. Mean baseline IOP ranged from 19.6 to 27.3 mm Hg (≥22 mm Hg in all trials except for the trials of patients with early untreated OAG).…”

“…One trial allowed various topical therapies, with a target IOP of 24 mm Hg or less or 20% or greater IOP reduction . The duration of follow-up ranged from 1.5 months to 120 months (>1 year in 10 trials). Four trials were rated good quality and 12 fair quality (eTable 10 in the Supplement).…”

A Synopsis of Recent Developments in Antiglaucoma Drugs

“…Metoprolol (3%) was as effective for five months as pilocarpine (2% and 4%) in glaucoma patients for without producing significant side effects or tachyphylaxis (104). A six week study of betaxolol (0.125%) in humans with ocular hypertension showed maintained reduction of IOP (105).…”

Screening for Glaucoma in Adults

“…Across all key questions, 83 studies (reported in 96 publications, total 75 887 participants) were included (30 trials and 53 diagnostic accuracy studies) (Figure 2). Sixteen studies were carried forward from the 2013 reviews, and 67 studies were new.…”

“…Seventeen trials (n = 4665) evaluated medical treatments for OAG vs placebo or no treatment . Nine trials were in the 2013 review and 8 trials were added (eTable 9 in the Supplement). Two trials enrolled patients with untreated, newly diagnosed OAG, 3 trials enrolled mixed populations (OAG or ocular hypertension, and 12 trials enrolled patients with ocular hypertension.…”

“…Nine trials were in the 2013 review and 8 trials were added (eTable 9 in the Supplement). Two trials enrolled patients with untreated, newly diagnosed OAG, 3 trials enrolled mixed populations (OAG or ocular hypertension, and 12 trials enrolled patients with ocular hypertension. Mean baseline IOP ranged from 19.6 to 27.3 mm Hg (≥22 mm Hg in all trials except for the trials of patients with early untreated OAG).…”

“…One trial allowed various topical therapies, with a target IOP of 24 mm Hg or less or 20% or greater IOP reduction . The duration of follow-up ranged from 1.5 months to 120 months (>1 year in 10 trials). Four trials were rated good quality and 12 fair quality (eTable 10 in the Supplement).…”

A Synopsis of Recent Developments in Antiglaucoma Drugs

“…Metoprolol (3%) was as effective for five months as pilocarpine (2% and 4%) in glaucoma patients for without producing significant side effects or tachyphylaxis (104). A six week study of betaxolol (0.125%) in humans with ocular hypertension showed maintained reduction of IOP (105).…”

Screening for Glaucoma in Adults

“…Across all key questions, 83 studies (reported in 96 publications, total 75 887 participants) were included (30 trials and 53 diagnostic accuracy studies) (Figure 2). Sixteen studies were carried forward from the 2013 reviews, and 67 studies were new.…”

“…Seventeen trials (n = 4665) evaluated medical treatments for OAG vs placebo or no treatment . Nine trials were in the 2013 review and 8 trials were added (eTable 9 in the Supplement). Two trials enrolled patients with untreated, newly diagnosed OAG, 3 trials enrolled mixed populations (OAG or ocular hypertension, and 12 trials enrolled patients with ocular hypertension.…”

“…Nine trials were in the 2013 review and 8 trials were added (eTable 9 in the Supplement). Two trials enrolled patients with untreated, newly diagnosed OAG, 3 trials enrolled mixed populations (OAG or ocular hypertension, and 12 trials enrolled patients with ocular hypertension. Mean baseline IOP ranged from 19.6 to 27.3 mm Hg (≥22 mm Hg in all trials except for the trials of patients with early untreated OAG).…”

“…One trial allowed various topical therapies, with a target IOP of 24 mm Hg or less or 20% or greater IOP reduction . The duration of follow-up ranged from 1.5 months to 120 months (>1 year in 10 trials). Four trials were rated good quality and 12 fair quality (eTable 10 in the Supplement).…”