Use of Aqueous Extract of Corn Silk in the Treatment of Urinary Tract Infection

Abstract

Aim: Worldwide about 150 million people were diagnosed with UTI each year. The increasing incidence of antibiotic resistance among bacterial pathogens necessitates medicinal plants as an alternate therapy in the management of UTI. Corn silk has been widely used as a folk medicine in Iraq. The aim of this study is to evaluate the clinical advantages of using the aqueous extract of corn silk in Iraqi patients with UTI. Method: This study was carried out on 42 patients of both sexes with age of 29.91±10.57 (mean±SD); who attend to outpatient clinic in Alkindy College of Medicine, Baghdad, Iraq, over the period from October 2011-March 2012; UTI is confirmed by defined symptoms together with laboratory results. Manifestation of UTI were checked clinically include suprapubic pain, urgency, frequency and dysuria; each symptom scored as follow: 0(none), 1(mild), 2(moderate), 3(severe) and 4(very severe). All of the patients were followed up after 5days, 10days and 20 days from starting course of treatment with aqueous extract of corn silk. Results: Administration of aqueous extract of corn silk to UTI patients result in significant P≤0.05 decreases in UTI symptoms after 5 days, 10 days and 20 days from starting the treatment compared to baseline values. The symptom score also showed significant reduction P≤0.05 reduction after 5, 10 and 20 days from starting the treatment. Conclusion: administration of aqueous extract of corn silk significantly reduce the symptoms in patient with UTI in addition to reduction in the values of pus cells, RBCs, and Crystals, without any reported side effect which indicate its efficacy and safety. [J Intercult Ethnopharmacol 2012; 1(2.000): 93-96

Evaluation of the Efficacy of Corn Silk and Vitamin D on Hyperlipidemia and Obesity in Experimental Rats

“…The dried material was ground by using a grinder, and then stored in a drying cabinet at 4±1°C until used. Corn silk tea extract (CSTE) was prepared separately by putting 72 mg of corn silk powder in boiled water (60 ml) for 15 min as mentioned by Sahib et al (2012). This extract was prepared freshly every day and given three times a day in a dose of 5 ml / rat by using a stomach tube.…”

A Study of Antibiotic Sensitivity and the Effect of Corn Silk Extract on the Bacteria that Isolated from Urine of hemodialysis Patients in Kirkuk city, Iraq

“…Fresh corn (Zea mays) were obtained from the local markets in Kirkuk city, and corn silk was separated from the rest of the corn and washed with distilled water and dried, by using filter papers and incubated at 40ºC for 5 days, then powdered.Then powdered material was dissolved in organic solvents namely ethanol and chloroform, and using of Agar well-diffusion method (Nessa et al, 2012;Sahib et al, 2012;AL-kufaishi and Al-Mashhedy, 2012;Hilmi et al, 2014;Morshed and Islam, 2015;Haslina and Eva, 2017).…”

“…It has been used against many pathogens and to treat urinary tract infections, as well as for treatment of high blood pressure and as a diuretic effect, and as previous researches suggested that it can be used to enhance immunity and treatment of bladder pain in people with urinary tract infection And to kill the germs causing itthrough the change of urines pH and not allowing the germs to adhesion to the cells (Sahib et al, 2012;Morshed and Islam 2015;Žilić et al, 2016;Haslina and Eva, 2017).…”

Unkomplizierte Harnwegsinfektionen: Extrakte aus ­Maisgriffeln (Zea mays L.) wirken gegen uropathogene E. coli

“…Eine klinische Untersuchung mit 42 eingeschlossenen Patienten mit UTI belegte eine signifikante Reduktion klinischer Symptome nach Anwendung wässriger Maisgriffelextrakte, verbunden mit einer Erythrozyten-und Leukozyten-Reduktion im Urin [12]. In-vitro-Untersuchungen zeigten antiinflammatorische Effekte eines hydroalkoholischen Maisgriffelextraktes, die auf eine verminderte Freisetzung von TNFα, einer verminderten bak teriellen LPS-induzierten Adhäsion von Monozyten an Endothelzellen und auf eine Hemmung interzellulärer Adhäsionsmoleküle (ICAM-1) zurückgeführt wurden [13].…”