Use of Antiemetic Agents in Acute Gastroenteritis

Abstract

Ondansetron therapy decreases the risk of persistent vomiting, the use of intravenous fluid, and hospital admissions in children with vomiting due to gastroenteritis. Future treatment guidelines should incorporate ondansetron therapy for select children with gastroenteritis.

Prevalence of Pediatric Gastroenteritis Disease in Al- Diwaniyah Governorate-Iraq

“…During the period of this study, a total of 723 patients admitted to the hospital, 616 patients of the infants and children under five years old were with diarrheal diseases represent (85.2%) of total hospitalization of children to the hospital, including 332 (53.9%) patients males and 284(46.1%) patients females .It was found that the incidence of infection in male is higher than in female, this is consistent with De Camp et al (14) , who indicated that the occurrence of infection is higher in males than females.Overall, lower infection 9.7 % was in infants represent 60 patients and the higher infection 63.6 % represents 392 patients was in children less than one year oldof all those less than five years old children admitted to the hospital with diarrhea compared to 164 patients which represent (26.7 %) in those above one to five years old (Table 1). The acute diarrhea cases were revealed the highest percentage of all cases(78.4 %) and (21.6 %) is for chronic cases.…”

Prevalence of Pediatric Gastroenteritis Disease in Al- Diwaniyah Governorate-Iraq

“…During the period of this study, a total of 723 patients admitted to the hospital, 616 patients of the infants and children under five years old were with diarrheal diseases represent (85.2%) of total hospitalization of children to the hospital, including 332 (53.9%) patients males and 284(46.1%) patients females .It was found that the incidence of infection in male is higher than in female, this is consistent with De Camp et al (14) , who indicated that the occurrence of infection is higher in males than females.Overall, lower infection 9.7 % was in infants represent 60 patients and the higher infection 63.6 % represents 392 patients was in children less than one year oldof all those less than five years old children admitted to the hospital with diarrhea compared to 164 patients which represent (26.7 %) in those above one to five years old (Table 1). The acute diarrhea cases were revealed the highest percentage of all cases(78.4 %) and (21.6 %) is for chronic cases.…”

Oral Ondansetron versus Domperidone for Acute Gastroenteritis in Pediatric Emergency Departments: Multicenter Double Blind Randomized Controlled Trial

“…Ondansetron reduces by over 50% the number of patients requiring IVT vs both domperidone and placebo (Table 2), in agreement with the results of other RCTs [15–19, 25]. Our results provide clear evidence of benefit of ondansetron also with respect to the other study outcomes.…”

The effect of antiemetics in childhood gastroenteritis

“…The findings in this systematic review are to a large extent in agreement with those reported by the Cochrane reviews [26] and previously done meta-analysis on the same subject [27-31]. Although we differ from the previously carried out reviews as we have only included studies looking at children aged 0 to 12 years and we have evaluated the quality of the studies and the outcomes based on the LiST model as suggested by CHERG intervention review process.…”

Prevalence of Pediatric Gastroenteritis Disease in Al- Diwaniyah Governorate-Iraq

“…During the period of this study, a total of 723 patients admitted to the hospital, 616 patients of the infants and children under five years old were with diarrheal diseases represent (85.2%) of total hospitalization of children to the hospital, including 332 (53.9%) patients males and 284(46.1%) patients females .It was found that the incidence of infection in male is higher than in female, this is consistent with De Camp et al (14) , who indicated that the occurrence of infection is higher in males than females.Overall, lower infection 9.7 % was in infants represent 60 patients and the higher infection 63.6 % represents 392 patients was in children less than one year oldof all those less than five years old children admitted to the hospital with diarrhea compared to 164 patients which represent (26.7 %) in those above one to five years old (Table 1). The acute diarrhea cases were revealed the highest percentage of all cases(78.4 %) and (21.6 %) is for chronic cases.…”

Oral Ondansetron versus Domperidone for Acute Gastroenteritis in Pediatric Emergency Departments: Multicenter Double Blind Randomized Controlled Trial

“…Ondansetron reduces by over 50% the number of patients requiring IVT vs both domperidone and placebo (Table 2), in agreement with the results of other RCTs [15–19, 25]. Our results provide clear evidence of benefit of ondansetron also with respect to the other study outcomes.…”

The effect of antiemetics in childhood gastroenteritis

“…The findings in this systematic review are to a large extent in agreement with those reported by the Cochrane reviews [26] and previously done meta-analysis on the same subject [27-31]. Although we differ from the previously carried out reviews as we have only included studies looking at children aged 0 to 12 years and we have evaluated the quality of the studies and the outcomes based on the LiST model as suggested by CHERG intervention review process.…”

Prevalence of Pediatric Gastroenteritis Disease in Al- Diwaniyah Governorate-Iraq

“…During the period of this study, a total of 723 patients admitted to the hospital, 616 patients of the infants and children under five years old were with diarrheal diseases represent (85.2%) of total hospitalization of children to the hospital, including 332 (53.9%) patients males and 284(46.1%) patients females .It was found that the incidence of infection in male is higher than in female, this is consistent with De Camp et al (14) , who indicated that the occurrence of infection is higher in males than females.Overall, lower infection 9.7 % was in infants represent 60 patients and the higher infection 63.6 % represents 392 patients was in children less than one year oldof all those less than five years old children admitted to the hospital with diarrhea compared to 164 patients which represent (26.7 %) in those above one to five years old (Table 1). The acute diarrhea cases were revealed the highest percentage of all cases(78.4 %) and (21.6 %) is for chronic cases.…”

Oral Ondansetron versus Domperidone for Acute Gastroenteritis in Pediatric Emergency Departments: Multicenter Double Blind Randomized Controlled Trial

“…Ondansetron reduces by over 50% the number of patients requiring IVT vs both domperidone and placebo (Table 2), in agreement with the results of other RCTs [15–19, 25]. Our results provide clear evidence of benefit of ondansetron also with respect to the other study outcomes.…”

The effect of antiemetics in childhood gastroenteritis

“…The findings in this systematic review are to a large extent in agreement with those reported by the Cochrane reviews [26] and previously done meta-analysis on the same subject [27-31]. Although we differ from the previously carried out reviews as we have only included studies looking at children aged 0 to 12 years and we have evaluated the quality of the studies and the outcomes based on the LiST model as suggested by CHERG intervention review process.…”