Use of an 800-nm Pulsed-Diode Laser in the Treatment of Recalcitrant Dissecting Cellulitis of the Scalp

Update on primary cicatricial alopecias

“…285,326,337,338 In isolated case reports, prolonged remission of disease for 1 year or more has been reported with isotretinoin gel (0.05%, used with 1% clindamycin gel for 8 weeks, followed by isotretinoin gel alone for 8 months, frequency not specified 339 ), zinc sulfate 326,340,341 (400 mg by mouth three times daily for 12 weeks, then 200 mg by mouth three times daily for 10 weeks 341 ), and oral steroids with low-dose alternate-day maintenance therapy. 323 Other options include oral and topical antibiotics (eg, tetracyclines, antistaphylococcal agents), antibacterial soaps and intralesional triamcinolone acetonide, which are variably effective when used as single agents or in combination 6,318,319,[322][323][324] ; dapsone, reportedly effective in severe, treatment-refractory disease (regimen unknown) by some 342 but not by others 285,343 ; and colchicine (0.6 g twice daily), which was moderately effective in 1 case. 343 Hydroxychloroquine, 285 methotrexate, 343 and ketoconazole 343 are ineffective on the basis of isolated reports.…”

“…323 Other options include oral and topical antibiotics (eg, tetracyclines, antistaphylococcal agents), antibacterial soaps and intralesional triamcinolone acetonide, which are variably effective when used as single agents or in combination 6,318,319,[322][323][324] ; dapsone, reportedly effective in severe, treatment-refractory disease (regimen unknown) by some 342 but not by others 285,343 ; and colchicine (0.6 g twice daily), which was moderately effective in 1 case. 343 Hydroxychloroquine, 285 methotrexate, 343 and ketoconazole 343 are ineffective on the basis of isolated reports. Successful treatment of the follicular occlusion triad in a woman, with minocycline and cyproterone acetate, an oral antiandrogen not available in the United States, has also been reported.…”

“…344 Incision and drainage of painful nodules 319 or excisional carbon dioxide laser with secondary intention healing 345 are among several surgical techniques presently advocated. Laser epilation using nonpulsed, non-Q-switched ruby 285 and 800-nm pulsed diode 343 modalities recently has been promoted as a therapeutic alternative in those with severe, treatment-refractory disease, but long-term follow-up is lacking and resignation of the patient to permanent hair loss and possible dyschromia is a concern.…”

Lasers and light-based therapies in ethnic skin: treatment options and recommendations for Fitzpatrick skin types V and VI

“…or adjunctive treatment of several hair disorders that are disproportionately prevalent in individuals of African ancestrypseudofolliculitis barbae, [11][12][13][14][15][16][17][18] acne keloidalis nuchae, 19,20 dissecting cellulitis of the scalp 21,22 and folliculitis decalvans. 23 When performing laser hair removal in individuals with richly pigmented skin, epidermal melanin acts as a competing chromophore and, therefore, the risk of adverse events from epidermal injury is greater than in lighter skin types.…”

What′s new in cicatricial alopecia?

“…Low dose corticosteroids [163] Colchicine [60,64] Dapsone [60,64] Excision and skin grafting [165,166] Lasers and radiotherapy [167,168,169] Acne keloidalis nuchae [82,228] First line Potent topical steroids [65,170] Oral antibiotics+topical steroids/intralesional triamcinolone [65,170] …”