2010
DOI: 10.1590/s1516-31802010000500009
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Use of albumin as a risk factor for hospital mortality among burn patients in Brazil: non-concurrent cohort study

Abstract: CONTEXT AND OBJECTIVE: Among burn patients, it is common to use colloidal substances under the justification that it is necessary to correct the oncotic pressure of the plasma, thereby reducing the edema in the burnt area and the hypotension. The aim here was to assess the risk of hospital mortality, comparing the use of albumin and crystalloid solutions for these patients. DESIGN AND SETTING: Non-concurrent historical cohort study at Faculdade de Medicina de Marília; within the Postgraduate program on Interna… Show more

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Cited by 12 publications
(9 citation statements)
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References 10 publications
(24 reference statements)
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“…[22] The effects of transfusion requirements in defining mortality risk factors in burns also were not studied considerably previously. In concomitant with our results, Caleman et al [23] defined the albumin transfusion requirement as a risk factor for mortality in burn patients. Lu et al [24] did not define the erythrocyte or plasma transfusion as a predictor of mortality in patients with a burn injury.…”
Section: Discussionsupporting
confidence: 88%
“…[22] The effects of transfusion requirements in defining mortality risk factors in burns also were not studied considerably previously. In concomitant with our results, Caleman et al [23] defined the albumin transfusion requirement as a risk factor for mortality in burn patients. Lu et al [24] did not define the erythrocyte or plasma transfusion as a predictor of mortality in patients with a burn injury.…”
Section: Discussionsupporting
confidence: 88%
“…Increase in serum albumin per unit has been reported to have a 12% lower CVD incidence risk over a three-year period among the elderly [20]. The associations between low albumin and all-cause mortality have also been reported consistently in previous studies [21,22,23,24]. …”
Section: Plasma Antioxidant Status and Cvdmentioning
confidence: 72%
“…For example, a non-concurrent historical cohort study that was carried out in Brazil based on DATASUS records found that use of albumin among patients with major burns was associated with considerably increased mortality (seven times higher than when crystalloid solutions were used). 40 The clinical evaluation on the effectiveness of intermediate outcomes for weight, diuresis and fluid balance parameters more directly related to the care process showed differences between the groups in this study. However, within clinical practice, these differences would probably not demonstrate observable relevance.…”
Section: Discussionmentioning
confidence: 57%