A case of tinea pedis caused by a dual infection with Trichophyton rubrum and Microsporum canis is reported. It is of particular interest because infections of the toe webs caused by M. canis are uncommon and the combination of T. rubrum and M. canis has not been reported.In addition, a marked difference in response to treatment with an imidazole (bifonazole) was observed.Microsporum canis infections between the toes and on the foot are very uncommon.Infections caused by two or more dermatophytes in the same skin area are not numerous in the literature, although undoubtedly more common than reported.Furthermore, the combination of M. canis with another dermatophyte cultured from a foot lesion was not found in our reference search. We describe a patient who had tinea pedis from which both T. rubrum and M. canis were isolated and whose Microsporum canis failed to respond to topical bifonazole.
CASE REPORTA 23-year-old male came to the Dermatology Clinic of the University of Texas Medical Branch suffering from mildly pruritic, inflammatory and scaly patches with minimal maceration involving the 3rd and 4th toe webs of both feet. He described this as a chronic problem which had run a stable course since its beginning about 8 months previously. He denied the use of any systemic or topical antifungal medications, A KOH preparation from a scraping of his lesion revealed hyphae and a culture from the lesion on Sabouraud agar with chloramphenicol and cycloheximide grew T. rubrum, confirmed by microscopic appearance and pigment production on corn meal agar. Various contaminant fungi were also present. After 7 days of treatment with bifonazole (as part of a therapeutic trial of this compound), a second culture was taken. Contaminants again were present and, in addition, a small colony suspected of