This research details the development of a design process and decision-making environment to support the acquisition of an air-based, interoperable, autonomous system-of-systems to support suppression of enemy air defenses missions. 12 The design is done using a three part process, which includes the concurrent development of the DoDAF products, modeling and simulation environment, and decision support environment. In particular, the research focuses on understanding how the interactions, interoperability, and autonomy level of the unmanned aircraft affect the overall mission performance.