Search citation statements
Paper Sections
Citation Types
Year Published
Publication Types
Relationship
Authors
Journals
Objective To describe the clinical and ultrasound characteristics of urinary bladder malignancies diagnosed on transvaginal ultrasound in women presenting with suspected gynecological problems. Methods This was a multicenter retrospective study of women with a histological diagnosis of urinary bladder malignancy that was suspected on transvaginal ultrasound examination. The cases were collected from three centers that specialize in the use of pelvic ultrasound and had been examined between January 2007 and October 2018. Clinical data were obtained from the computer databases and all tumor images were assessed by two of the authors (D.J. and J.K.) to identify characteristic sonographic patterns. We compared the characteristics of tumors between women presenting with symptoms suspicious of urinary bladder malignancy and those without such symptoms. Results Thirty women with a confirmed diagnosis of urinary bladder malignancy on histological examination were included. Median age at diagnosis was 70.5 (range 36–88) years. The most common presenting symptom was postmenopausal bleeding, which was recorded in 18 (60%) women. Ten (33%) women had symptoms suspicious of bladder malignancy, of whom six had unexplained visible hematuria, three had unexplained recurrent urinary tract infections and one had dysuria and microhematuria. On histological examination, 23 (77%) women were diagnosed with primary bladder malignancy whilst seven (23%) had metastases in the bladder from other primary tumors. Out of 23 primary tumors, 21 (91%) were of urothelial origin (12 low grade and nine high grade). Most low‐grade urothelial carcinomas appeared on ultrasound as irregular papillary growth (11/12, 92%) and were moderately to highly vascular on color Doppler examination (8/12, 67%). The ultrasound appearances of primary non‐urothelial and metastatic tumors varied, without a clear common morphological tumor pattern. The tumors found in women with symptoms suggestive of bladder malignancy did not differ unequivocally from those detected in other women in terms of size, ultrasound morphology, vascularity or histological type. Conclusion Urinary bladder malignancies can be detected in patients undergoing transvaginal ultrasound examination for suspected gynecological problems. Primary urothelial cancers have a relatively uniform morphological pattern, whilst the appearances of other bladder malignancies are more variable. Copyright © 2019 ISUOG. Published by John Wiley & Sons Ltd.
Objective To describe the clinical and ultrasound characteristics of urinary bladder malignancies diagnosed on transvaginal ultrasound in women presenting with suspected gynecological problems. Methods This was a multicenter retrospective study of women with a histological diagnosis of urinary bladder malignancy that was suspected on transvaginal ultrasound examination. The cases were collected from three centers that specialize in the use of pelvic ultrasound and had been examined between January 2007 and October 2018. Clinical data were obtained from the computer databases and all tumor images were assessed by two of the authors (D.J. and J.K.) to identify characteristic sonographic patterns. We compared the characteristics of tumors between women presenting with symptoms suspicious of urinary bladder malignancy and those without such symptoms. Results Thirty women with a confirmed diagnosis of urinary bladder malignancy on histological examination were included. Median age at diagnosis was 70.5 (range 36–88) years. The most common presenting symptom was postmenopausal bleeding, which was recorded in 18 (60%) women. Ten (33%) women had symptoms suspicious of bladder malignancy, of whom six had unexplained visible hematuria, three had unexplained recurrent urinary tract infections and one had dysuria and microhematuria. On histological examination, 23 (77%) women were diagnosed with primary bladder malignancy whilst seven (23%) had metastases in the bladder from other primary tumors. Out of 23 primary tumors, 21 (91%) were of urothelial origin (12 low grade and nine high grade). Most low‐grade urothelial carcinomas appeared on ultrasound as irregular papillary growth (11/12, 92%) and were moderately to highly vascular on color Doppler examination (8/12, 67%). The ultrasound appearances of primary non‐urothelial and metastatic tumors varied, without a clear common morphological tumor pattern. The tumors found in women with symptoms suggestive of bladder malignancy did not differ unequivocally from those detected in other women in terms of size, ultrasound morphology, vascularity or histological type. Conclusion Urinary bladder malignancies can be detected in patients undergoing transvaginal ultrasound examination for suspected gynecological problems. Primary urothelial cancers have a relatively uniform morphological pattern, whilst the appearances of other bladder malignancies are more variable. Copyright © 2019 ISUOG. Published by John Wiley & Sons Ltd.
Carcinoma in situ (CIS) of the bladder poses a clinical challenge to urologists worldwide. The clinical course of CIS ranges from benign, indolent tumor growth to highly progressive tumor proliferation with deleterious effects on patient outcome and increased disease-specific mortality. The aim of our review was to outline the natural history of bladder CIS in a single concise source for young urologists. We performed a PubMed review of the literature on CIS of the bladder. We used CIS, BCG and superficial bladder cancer as the keywords for our search. Following a group discussion, the authors selected 77 important publications to be included in our review article. The presence of bladder CIS increases the risk of panurothelial disease involving the prostate, urethra or upper urinary tracts. Urine cytology is the primary approach for the diagnosis of CIS. Intravesical BCG remains the gold standard for the initial treatment of CIS. Early radical cystectomy for cases that present BCG failure showed a higher rate of success with long-term cure. Frozen section biopsy of the distal ureter should be performed when CIS of the bladder has been preoperatively diagnosed. Whether frozen section biopsy was performed and regardless of the condition of the distal ureter at the time of cystectomy, postoperative follow-up with cytology, endoscopy of the new pouch and ureteroscopy of the ureters is recommended for early detection of possible recurrence. ÖZETMesanede karsinoma in situ (KIS) tüm dünyada ürologlar için bir klinik sorun oluçturmaktadir Tembel bir tümörden, hastanin akibeti üzerine zararli etki ve hastahga özgü mortalité artiçi ile birlikte oldukça progresif bir tümöre kadar degiçen geni § bir klinik seyre sahiptir. Derlememizin amaci genç ürologlann mesane KIS'in dogal seyrini anlamalari için özet bir kaynak saglamaktir. Mesane KIS çaliçilan literatürlerin bir pubmed derlemesini yaptik. Tarama sirasinda anahtar sözcükler olarak "CIS", "BCG" ve "superficial bladder cancer" kullandik. Grup tartiçmasini takiben, yazarlar 77 önemli yayinm derleme makalemize dahil edilmesine karar verdi. Mesane KIS mevcudiyeti prostat, uretra veya üst idrar yollarini tutan panurotelial hastalik riskini artirmaktadir. Îdrar sitolojisi KIS tanisi için baçlica dayanaktir. întravezikal BCG KIS ba §langiç tedavisi için altin Standart olmayi sürdürmektedir. BCG'nin ba §ansiz oldugu olgular için erken radikal sistektomi uzun dönemli kür oraniari ile daha yüksek ba §an göstermi §tir. Mesanede KIS tanisi ameliyat öncesi konuldugunda, distal ureterin (frozen section) biyopsisi yapilmalidir Sistektomi sirasinda distal ureterin durumuna veya frozen kesit yapilip yapilmadigma bakilmaksizin, olasi rekürrensin erken saptanmasi için sitoloji, yeni kesenin endoskopisi ve ureterlerin ureteroskopisi ile ameliyat sonrasi takip önerilmektedir. Anahtar sözcükler: BCG; karsinoma in situ; intravezikal kemoterapi
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.