Biochemical Pharmacology volume 80, issue 3, P289-296 2010 DOI: 10.1016/j.bcp.2010.03.032 View full text
Sowmya Venkatasubramanian, David E. Newby, Ninian N. Lang

Abstract: Despite modern advances in the treatment of the causes and consequences of cardiovascular illness, heart disease and heart failure remain a leading cause of death in the western world. Many novel peptides are emerging as biomarkers and potential therapeutic tools for this debilitating condition. Urocortins represent one such group of peptides whose role in normal cardiovascular physiology and disease states is now increasingly being recognized. The cardiovascular effects of the urocortins are mediated via cort…

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