1999
DOI: 10.1001/archderm.135.4.400
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Urinary Porphyrin Excretion in a Human Population Highly Exposed to Hexachlorobenzene

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Cited by 24 publications
(21 citation statements)
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“…Although the heptaporphyrin fraction is present most frequently in exposed populations, we found no evidence of a relationship between the presence of this porphyrin and HCB concentrations in blood. This lack of association between urinary porphyrin excretion and HCB levels has been observed previously in adults of the same population (17).…”
Section: Discussionsupporting
confidence: 68%
See 1 more Smart Citation
“…Although the heptaporphyrin fraction is present most frequently in exposed populations, we found no evidence of a relationship between the presence of this porphyrin and HCB concentrations in blood. This lack of association between urinary porphyrin excretion and HCB levels has been observed previously in adults of the same population (17).…”
Section: Discussionsupporting
confidence: 68%
“…No association between HCB serum concentrations and total urinary porphyrin excretion was found. The porphyrin profile of the highly exposed subjects was normal (17). Analysis of HCB metabolism and excretion in urine and feces revealed a strong correlation between HCB serum concentrations and pentachlorobenzenetiol (PCBT) in urine (18) and unmetabolized HCB (19).…”
mentioning
confidence: 99%
“…In Spain, factory workers chronically exposed to HCB and residents near the factory had serum HCB levels that were 150 to 50 times higher, respectively, than the limits of detection (on a whole weight basis) in NHANES 1999(Herrero et al, 1999. Residency near industrial or agricultural areas has been associated with higher serum HCB levels (Barber et al, 2005;Bradman et al, 2006).…”
Section: Age Groupmentioning
confidence: 99%
“…The population studied was also exposed to several other organochlorine compounds, but the relative levels were much lower than those of HCB. In addition, a crosssectional study was also performed in Flix (Herrero et al, 1999). Although elevated HCB levels were detected in all serum samples (values ranging from 1.1 to 1616 ng/mL, mean = 40 ng/mL), there was no association between the HCB concentrations and porphyrin levels for the 604 study participants.…”
Section: Humansmentioning
confidence: 97%