Uric Acid and Creatinin in the Urine of Infants

Abstract

Medical literature abounds with publications concerning the uric acid excretion and its variations in relation to diet and to conditions of health and disease. Pediatric literature, however, gives but little information on the excretion of uric acid by infants. This is due chiefly to the difficulties encountered in collecting the infant's urine quantitatively. The published data we have found are summary and incomplete, and are often contradictory. The discrepancies apparent are probably referable to inaccurate measurements. Until quite recently, the methods for determining uric acid have not been satisfactorily dependable.We find that Lesn\l=e'\and Binet,1 in their publication, state that one can find 0.15 gm. of uric acid excreted in the urine of infants in twenty\x=req-\

The Creatinine Coefficient in the Infant

“…of body-weight in 24 hours. THE CRE.ATININE COEFFICIENT IN TIHE INFANT *In a previous paper (7), and concurrently with the question of uric acid excretion in the infant, I have dealt with the rate at which creatinine is eliminated in the urine. The cases studied comprised both normal and undernouirished infants.…”