Upper airway compromise secondary to edema in Graves’ disease

Shan, William Li Pi; Hatzakorzian, Roupen; Sherman, Mark; Backman, Steven B.

doi:10.1007/bf03021825

Cited by 3 publications

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the light of a previous report by Li Pi et al [9], we also think that the respiratory difficulty in our patient may have also been due to the primary infiltrative process similar to Graves' ophthalmopathy and dermopathy potentially causing upper airway edema. Additionally, retrosternal goiter compression of venous drainage may have also contributed to the edema formation.…”

Section: Discussionsupporting

confidence: 67%

“…Recently, Li Pi et al published the only report stating that uncontrolled hyperthyroid patients with large goiters secondary to Graves' disease may develop edema of the upper airway [9]. Since the larynx and vocal cords of the patient were found to be edematous during the difficult intubation process, this may be regarded as the cause of the respiratory arrest.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Fetal death due to upper airway compromise complicated by thyroid storm in a mother with uncontrolled Graves' disease: a case report

et al. 2009

View full text Add to dashboard Cite

IntroductionWe report an unusual case of upper airway compromise complicated by thyroid storm in a pregnant woman with Graves' disease, ending with the in utero death of the fetus. This complication might have developed due to upper airway edema as a result of poorly controlled hyperthyroidism.Case presentationA 41-year-old Turkish woman at 27 weeks' gestation suffering from Graves' disease was referred to our emergency department with a diagnosis of respiratory arrest. She was unconscious and had been intubated. Her laboratory results were compatible with thyrotoxicosis. The patient had suffered from respiratory difficulty for a long time and had stopped using her antithyroid medications after the first trimester of pregnancy. One day before, she had visited an obstetrician because her respiratory distress had increased. At that time, her fetus was still alive. She was given oxygen therapy and then sent home. With a presumptive diagnosis of thyroid storm, she was admitted to the intensive care unit and treated with aggressive medical therapy. The baby was found to be no longer alive and was delivered vaginally after labor induction. The mother was discharged 10 days later with maintenance therapy.ConclusionHyperthyroidism during pregnancy warrants very close attention and should almost always be treated with appropriate antithyroid medications. Maternal respiratory distress in such patients can be an early sign of impending upper airway compromise and thyroid storm, which can endanger the mother and fetus unless prompt and aggressive therapy is initiated.

show abstract

Section: Discussionsupporting

confidence: 67%

Section: Discussionmentioning

confidence: 99%

Fetal death due to upper airway compromise complicated by thyroid storm in a mother with uncontrolled Graves' disease: a case report

et al. 2009

View full text Add to dashboard Cite

show abstract

Broken heart syndrome triggered by an obstructive goiter not associated with thyrotoxicosis

Hatzakorzian

Bui

Schricker

et al. 2013

Can J Anesth/J Can Anesth

Self Cite

View full text Add to dashboard Cite

Caracterização vocal de pacientes com hipertireoidismo e hipotireoidismo

Isolan-Cury¹,

Silva

Monte

et al. 2007

Rev. soc. bras. fonoaudiol.

View full text Add to dashboard Cite

OBJETIVO: Caracterizar a qualidade vocal, por meio de análise computadorizada e perceptivo-auditiva, de pacientes com hipertireoidismo (grupo A) e hipotireoidismo (grupo B). MÉTODOS: Vinte mulheres não fumantes, com idades entre 18 e 55 anos, atendidas no Ambulatório de Endocrinologia da instituição, foram avaliadas após o diagnóstico clínico e laboratorial de hipertireoidismo ou hipotireoidismo. Os parâmetros investigados foram: tempo da doença, presença de queixa vocal, tempos máximos de fonação /a/, /s/ e /z/, freqüência fundamental (F0), ruído glótico (GNE). Os aspectos avaliados na análise perceptivo-auditiva, foram: coordenação pneumo-fonoarticulatória (coordenada ou incoordenada), pitch, loudness, ataque vocal, ressonância, velocidade de fala e qualidade vocal, que poderia ter até duas das seguintes classificações: neutra, rouca, soprosa, áspera ou tensa, e grau: leve, moderado ou severo. Os dados foram tabulados e analisados estatisticamente através do programa EPI-INFO 6.04b, método qualitativo Fisher, com nível de significância menor do que 0.05. RESULTADOS: A análise perceptivo-auditiva mostrou que sete pacientes hipotireoideos e nove pacientes hipertireoideos apresentaram alteração na qualidade vocal. Oito pacientes em ambos os grupos apresentaram incoordenação pneumo-fonoarticulatória. Oito pacientes do grupo A e seis pacientes do grupo B referiam queixas vocais como rouquidão e voz grossa, respectivamente. Na análise acústica, nove pacientes apresentaram o ruído glótico alterado. CONCLUSÃO: Os resultados evidenciaram grande incidência de alteração vocal nos grupos estudados (grupos dos pacientes com hipertireoidismo e com hipotireoidismo), o que demonstra a relação entre disfonia e disfunções tireoideanas.

show abstract

Upper airway compromise secondary to edema in Graves’ disease

Cited by 3 publications

References 14 publications

Fetal death due to upper airway compromise complicated by thyroid storm in a mother with uncontrolled Graves' disease: a case report

Fetal death due to upper airway compromise complicated by thyroid storm in a mother with uncontrolled Graves' disease: a case report

Broken heart syndrome triggered by an obstructive goiter not associated with thyrotoxicosis

Caracterização vocal de pacientes com hipertireoidismo e hipotireoidismo

Contact Info

Product

Resources

About