Update on the Practical Role of Echocardiography in Selection, Implantation, and Management of Patients Requiring Left Ventricular Assist Device Therapy

Katapadi, Aashish; Umland, Matt M.; Khandheria, Bijoy K.

doi:10.1007/s11886-022-01771-9

Cited by 3 publications

(2 citation statements)

References 54 publications

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“…With echocardiography, the heart can be displayed in motion, in color, and in M-mode type to accompany the heartbeat. In this way, cardiac echocardiography can be performed successfully with transthoracic application, and it is possible to obtain better resolution with transesophageal application, which increases penetration (21). Indications for cardiac ultrasonography evaluation (Echocardiography) in intensive care are targeted and summarized in Table 2 (22,23).…”

Section: Cardiac Ultrasound (Echocardiography)mentioning

confidence: 99%

Lung and cardiac ultrasonography in intensive care

DOĞANAY¹,

Yılmaz²,

Soylu³

2022

Kastamonu Med J

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Ultrasonography is an imaging tool that is increasingly used in the diagnosis and follow-up of many lung and heart diseases. Full lung ultrasonography is the examination of both hemithorax and protocols and image definitions have been created to make the examination more systematic and accurate. Cardiac ultrasonography is used to evaluate a moving organ. It requires users to be able to detect and interpret dynamic and variable values. Another feature of ultrasonography is its ability to guide interventional procedures. Ultrasonography will develop in the future and will be used more as a modern diagnostic tool in lung and heart evaluation by specialists.

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Section: Cardiac Ultrasound (Echocardiography)mentioning

confidence: 99%

Lung and cardiac ultrasonography in intensive care

DOĞANAY¹,

Yılmaz²,

Soylu³

2022

Kastamonu Med J

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“…RV function also plays a critical role in the selection of patients with HF for the left ventricular assist device (LVAD) implantation, as it is the RV that experiences increased stress following device implantation. It has been shown that the RV does not remodel after implantation and RV failure is the most common complication, causing significant mortality in the postoperative period [ 10 ]. It has also been shown that patients with HF who had an improvement in RV function at 40-month follow-up, as measured by TAPSE, had increased survival compared to those whose RV function deteriorated or did not change [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Right Ventricle Remodelling in Left-Sided Heart Failure in Rats: The Role of Calcium Signalling

et al. 2022

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Right ventricular dysfunction (RVD) can follow primary pulmonary diseases, but the most common cause of its development is left-sided heart failure (HF). RVD is associated with HF progression, increased risk of death and hospitalisation. The mechanism of right ventricle (RV) remodelling leading to RVD due to left-sided HF is not fully elucidated. Rats underwent LAD ligation to induce extensive left ventricle (LV) myocardial infarction (MI) and subsequent left-sided HF. Sham-operated animals served as controls. After 8 weeks of follow-up, the animals underwent LV and RV catheterisation, and systolic function and intracellular Ca2+ signalling were assessed in cardiomyocytes isolated from both ventricles. We demonstrated that rats with LV failure induced by extensive LV myocardial infarction also develop RV failure, leading to symptomatic biventricular HF, despite only mildly increased RV afterload. The contractility of RV cardiomyocytes was significantly increased, which could be related to increased amplitude of Ca2+ transient, preserved SERCA2a activity and reduced Ca2+ efflux via NCX1 and PMCA. Our study indicates that RV failure associated with post-MI LV failure in a rat model cannot be explained by a decline in cardiomyocyte function. This indicates that other factors may play a role here, pointing to the need for further research to better understand the biology of RV failure in order to ultimately develop therapies targeting the RV.

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Multimodality imaging for the evaluation and management of patients with long-term (durable) left ventricular assist devices

Cameli,

Aboumarie,

Pastore

et al. 2024

European Heart Journal - Cardiovascular Imaging

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Left ventricular assist devices (LVADs) are gaining increasing importance as therapeutic strategy in advanced heart failure (HF), not only as bridge to recovery or to transplant, but also as destination therapy. Even though long-term LVADs are considered a precious resource to expand the treatment options and improve clinical outcome these patients, these are limited by peri-operative and post-operative complications, such as device-related infections, haemocompatibility-related events, device mispositioning and right ventricular failure. For this reason, a precise pre-operative, peri-operative and post-operative evaluation of these patients is crucial for the selection of LVADs candidates and the management LVADs recipients. The use of different imaging modalities offers important information to complete the study of patients with LVADs in each phase of their assessment, with peculiar advantages/disadvantages, ideal application and reference parameters for each modality. This clinical consensus statement sought to guide the use of multimodality imaging for the evaluation of patients with advanced HF undergoing LVADs implantation.

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Update on the Practical Role of Echocardiography in Selection, Implantation, and Management of Patients Requiring Left Ventricular Assist Device Therapy

Cited by 3 publications

References 54 publications

Lung and cardiac ultrasonography in intensive care

Lung and cardiac ultrasonography in intensive care

Right Ventricle Remodelling in Left-Sided Heart Failure in Rats: The Role of Calcium Signalling

Multimodality imaging for the evaluation and management of patients with long-term (durable) left ventricular assist devices

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