volume 39, issue 1, P69-72 2011
DOI: 10.1016/j.jcms.2010.03.022
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Sophie C.C. Kuijpers, Erik W. van Roessel, J.P. Richard van Merkesteyn

Abstract: Bisphosphonates are used in the management of metastatic bone disease, Paget's disease of bone and osteoporosis. A long-term complication of these drugs is bisphosphonate-related osteonecrosis of the jaws (BRONJ). Treatment of BRONJ can be quite challenging, and remains a topic of debate. We report the case of a 74-year-old woman who had used Fosamax(®) (alendronate sodium) orally for four years. After 3½ years she developed pain, swelling, and a fistula in the left mandible. After exploration and sequestrecto…

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