Universal DNA detection realized by peptide based carbon nanotube biosensors

Li, Wenjun; Gao, Yubo; Zhang, Jiaona; Wang, Xiaofang; Yin, Feng; Li, Zigang; Zhang, Min

doi:10.1039/c9na00625g

Cited by 30 publications

(10 citation statements)

References 51 publications

(56 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…141 Zhang et al firstly utilized a peptide as a DNA sensing element and built a novel CNT-DNA thin-film-transistor sensor. 142 Different from the former known DNA bio-detector and NanoDrop, this bioinspired sensor had a broader sensing range of 1.6 Â 10 À4 to 5 Â 10 À6 M (the detection limit was 0.88 mg L À1 ). In 2015, Wang et al firstly found that carboxyl-functionalized SWCNHs (SWCNHs-COOH) had peroxidase-like activity similar to natural peroxidase.…”

Section: Bioengineeringmentioning

confidence: 99%

Bioinspired carbon nanotube-based materials

et al. 2022

View full text Add to dashboard Cite

show abstract

Section: Bioengineeringmentioning

confidence: 99%

Bioinspired carbon nanotube-based materials

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Schematic representation of the analytical protocol and detection is represented in Figure 26B. It is also possible to fabricate CNT based devices for sensing any kind of DNA sequence [490]. To achieve this result, authors functionalized CNTs with a specific peptide (with the sequence Fmoc-RRMEHRMEW) as natural molecules having the unique ability to selec- The sensitivity of the sensor was 4 × 10 13 molecules/cm 2 .…”

Section: Carbon Nanotube Sensingmentioning

confidence: 99%

Carbon Nanomaterials: Synthesis, Functionalization and Sensing Applications

Speranza

2021

Nanomaterials

175

View full text Add to dashboard Cite

Recent advances in nanomaterial design and synthesis has resulted in robust sensing systems that display superior analytical performance. The use of nanomaterials within sensors has accelerated new routes and opportunities for the detection of analytes or target molecules. Among others, carbon-based sensors have reported biocompatibility, better sensitivity, better selectivity and lower limits of detection to reveal a wide range of organic and inorganic molecules. Carbon nanomaterials are among the most extensively studied materials because of their unique properties spanning from the high specific surface area, high carrier mobility, high electrical conductivity, flexibility, and optical transparency fostering their use in sensing applications. In this paper, a comprehensive review has been made to cover recent developments in the field of carbon-based nanomaterials for sensing applications. The review describes nanomaterials like fullerenes, carbon onions, carbon quantum dots, nanodiamonds, carbon nanotubes, and graphene. Synthesis of these nanostructures has been discussed along with their functionalization methods. The recent application of all these nanomaterials in sensing applications has been highlighted for the principal applicative field and the future prospects and possibilities have been outlined.

show abstract

“…Replacing silicon with CNTs overcomes this scaling limit allowing for much smaller devices with the current limit being approximately 40 nm (Q. Cao et al, 2017; S. Liu & Guo, 2012). CNTs were first used within a FET device in 2000 by Dai's group (Kong et al, 2000); since then it has been shown that CNT‐FET devices can detect biological molecules both label‐free and labeled with recognition elements with detection limits as low as 0.88 μg L −1 (W. Li, Gao, et al, 2020). CNTs are an ideal material for the channel in FETs as not only are they semi‐conducting and easily modified but they are extremely sensitive to the electrical properties of their environment (Artyukhin et al, 2006) making them an ideal sensing element.…”

Section: Understanding Biology Using Nanowiresmentioning

confidence: 99%

Toward nanobioelectronic medicine: Unlocking new applications using nanotechnology

Gibney

Hicks

Robinson

et al. 2021

WIREs Nanomed Nanobiotechnol

View full text Add to dashboard Cite

Bioelectronic medicine aims to interface electronic technology with biological components and design more effective therapeutic and diagnostic tools. Advances in nanotechnology have moved the field forward improving the seamless interaction between biological and electronic components. In the lab many of these nanobioelectronic devices have the potential to improve current treatment approaches, including those for cancer, cardiovascular disorders, and disease underpinned by malfunctions in neuronal electrical communication. While promising, many of these devices and technologies require further development before they can be successfully applied in a clinical setting. Here, we highlight recent work which is close to achieving this goal, including discussion of nanoparticles, carbon nanotubes, and nanowires for medical applications. We also look forward toward the next decade to determine how current developments in nanotechnology could shape the growing field of bioelectronic medicine. This article is categorized under: Therapeutic Approaches and Drug Discovery > Emerging Technologies Nanotechnology Approaches to Biology > Nanoscale Systems in Biology Diagnostic Tools > Biosensing

show abstract

Universal DNA detection realized by peptide based carbon nanotube biosensors

Abstract: Although DNA recognition has been achieved using numerous biosensors with various sensing probes, the utilization of bio-interaction between DNA and biomolecules has seldom been reported in universal DNA detection.

Cited by 30 publications

References 51 publications

Bioinspired carbon nanotube-based materials

Bioinspired carbon nanotube-based materials

Carbon Nanomaterials: Synthesis, Functionalization and Sensing Applications

Toward nanobioelectronic medicine: Unlocking new applications using nanotechnology

Contact Info

Product

Resources

About